Berberine Sulfate powder bulk supplier

Berberine Sulfate powder

CAS: 6190-33-6

MF: C40H42N2O15S

MW: 822.83

EINECS: 211-195-9

Specification: 99% min Berberine Sulfate powder

Sample: Berberine Sulfate powder Avaliable

Packaging: 1kg/bag, 25kg/drum

Brand: Ausreson

MOQ: 1 kg

Appearance: white powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

1. What is Berberine Sulfate Powder?

Berberine Sulfate is a quaternary ammonium salt isolated from premium botanical sources such as Berberis aristata (Indian Barberry) or Coptis chinensis.

Through a precise, GMP-certified isolation process, the natural berberine alkaloid is reacted with sulfuric acid rather than hydrochloric acid. This structural variation yields a distinct crystalline form that offers unique advantages in specific delivery systems.

Technical Specification Overview (Standard USP/EP Grade)

2. Berberine Sulfate vs. Berberine HCl: 

The primary question R&D managers ask is: Why choose the sulfate form over the hydrochloride form? The answer lies in solubility and structural stability in liquid matrices.

Enhanced Water Solubility: Berberine Sulfate exhibits significantly higher water solubility at body temperature compared to Berberine HCl. This makes it the preferred raw material for liquid-filled hard capsules, functional beverages, and clean-label shots where precipitation or grittiness is a deal-breaker.

Reduced Gastric Irritation Potential: Some pharmacokinetics literature suggests that the sulfate anion is gentler on the gastric mucosa during large-dose oral intake, which helps brands mitigate consumer complaints regarding digestive discomfort—a common issue with standard berberine products.

Because of its distinct physical properties, wholesale Berberine Sulfate powder is highly versatile across modern clean-label manufacturing lines:

Two-Piece Hard Capsules (Vegetarian): Excellent flowability makes it ideal for automatic encapsulation lines using HPMC capsules, minimizing machine downtime and static cling.

Liquid Delivery Systems & Tinctures: Due to its superior solubility profile, it integrates smoothly into clear liquid formulations without heavy sediment.

Complex Metabolic Health Blends: Pairs synergistically in solid dosage forms with Chromium Picolinate, Alpha-Lipoic Acid (ALA), or Cinnamon Extract.

4. Overcoming Supply Chain Risks:

Rigorous Identification Testing: Utilizing high-performance liquid chromatography (HPLC) combined with thin-layer chromatography (TLC) to prove 100% plant-based origin and eliminate synthetic adulteration.

Pesticide and Solvent Residue Screening: Completely free of any harmful chemical residues, complying with United States Pharmacopeia (USP) <467> standards for solvent residues and EU EC No 396/2005 regulations on pesticide residue limits.

Microbial Control: Employing advanced radiation-free sterilization methods to ensure extremely low total bacterial count (TPC) while maintaining the integrity of the active ingredients.

Partner with a Certified Berberine Sulfate Producer

Launching a high-quality, compliant product requires a raw material partner who understands Western market standards. We offer fully documented, GMP-compliant bulk berberine sulfate powder, third-party tested, designed for automated capsule and liquid production.

Contact our technical sales team today to request a Certificate of Analysis (CoA), Safety Data Sheet (SDS), or free working samples for your R&D lab.

About us

Private Label design, fast delivery, USA Warehouse, European Warehouse, capsules factory,Softgels factory,tablets factory, pills factory, Gummies factory, Liquid Drops factory,Gum factory,solid beverage factory, customized factory, capsules manufacturer,Softgels manufacturer, tablets manufacturer, pills manufacturer, Gummies manufacturer, Liquid Drops manufacturer,Gum manufacturer,solid beverage manufacturer, customized manufacturer.

Our advantage

We possess extensive experience, handling every step from sourcing each ingredient in the formulation to post-filling inspection, all at the most competitive prices and with the fastest delivery times.

InterlGroup owns factory, Main Product Foods additives, Nutritional supplements, Healthcare Products(capsules,Softgels,tablets,Gummies,Liquid Drops,Gum,solid beverage and other customized products), plant extracts.

Support OEM&ODM service，Design label packaging, Overseas in stock, Fast customization, Drop Shipping.

Intergroup is supplying OEM service for the Well-known brands Reson and Ausreson. 

Alibaba International Station No.1 supplier,  Alibaba International Station Number 1, Alibaba International Station Number one.