Esculin Powder 98% supplier | High-Purity Horse Chestnut Extract

Esculin powder

CAS: 531-75-9

MF: C₁₅H₁₆O₉

MW: 340.28

EINECS: 610-504-8

Specification: 99% min Esculin powder

Sample: Esculin powder Avaliable

Packaging: 1kg/bag, 25kg/drum

Brand: Ausreson

MOQ: 1 kg

Appearance: white powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

What Is Quercetin Powder? 

Quercetin (also spelled Aesculin, CAS No. 531-75-9) is a naturally occurring coumarin glycoside primarily extracted from the bark and seeds of the horse chestnut (Aesculus hippocastanum).

Unlike crude horse chestnut extracts, which are typically standardized to aescin (a triterpene saponin), isolated aescin powder is specifically targeted for the vascular support properties of this glycoside.

Key Technical Specifications for B2B Procurement:

• General Specification: 98% (HPLC, High-Performance Liquid Chromatography)
• Appearance: White to off-white fine crystalline powder
• Solubility: Sparingly soluble in water, soluble in hot water and hot alcohol, readily soluble in alkaline solutions.

Key Applications:

1. Microcirculation and Vascular Integrity (Nutritional Supplements)

In the U.S. and European markets, sedentary lifestyles and an aging population have driven a surge in demand for products that support the circulatory system. Esculin acts at the cellular level to:

Enhance capillary tone and reduce permeability.

Inhibit enzymes that break down structural proteins in blood vessel walls.

Provide potent antioxidant support to combat oxidative stress in vascular tissues.

2. Redness Reduction and Dark Circle Fading (Derma-Cosmetics)

In high-end topical skincare formulations, esculin is highly sought after due to its precise mechanism of action:

• Eye Care: Improves the appearance of dark circles and puffiness by promoting local microcirculation.
• Skin Soothing: Helps improve skin redness and conditions prone to telangiectasia by alleviating capillary fragility.

Dosage Forms and Best Practices for Manufacturing

1. Hard Capsules/Vegetarian Capsules (Solid Dosage Forms)

Advantages: This is the preferred dosage form for dietary supplements in Europe and the United States. Hard capsules protect the crystalline structure and prevent premature degradation caused by moisture.

Formulation Notes: Due to its bitter taste, using a capsule dosage form completely avoids compliance issues related to consumer palatability. Combining quercetin with synergistic plant extracts (such as vitamin C or bioflavonoids) can enhance the product’s market competitiveness.

2. Tablets

Reason for Use: Ideal for cost-effective, large-scale production.

Formulation Notes: The R&D team must monitor tableting pressure to ensure the crystal structure of high-purity quercetin remains intact; otherwise, dissolution rates may be compromised.

3. Topical Lotions and Serums (Cosmetics)

Reason for Suitability: Ideal for targeted skincare.

Formulation Considerations: Since quercetin is slightly soluble in cold water but highly soluble in alkaline or hot water solutions, formulators must carefully control pH and temperature during the oil-in-water emulsion process to prevent crystallization in the final cream or serum.

Evaluating Horse Chestnut Powder Suppliers:

When sourcing from global manufacturing partners, quality assurance teams in Europe and the United States require rigorous validation. Please ensure your supplier can provide:

• Complete traceability: Comprehensive documentation of the entire process, from the harvesting of raw horse chestnut (Aesculus hippocastanum) material to the final extraction.
• Third-Party Testing: Validated high-performance liquid chromatography (HPLC) testing to confirm purity (≥98%) and strict compliance with United States Pharmacopeia (USP)/European Pharmacopoeia (EP) limits for heavy metals, residual solvents, and microbial contamination.
• International certifications: Select facilities compliant with GMP (Good Manufacturing Practice), ISO 22000, and Clean Label certifications (meeting Kosher/Halal standards).

Conclusion:

Incorporating high-purity aesculin powder into your product line will help your brand capitalize on the growing demand in Western markets for scientifically validated plant-based health solutions. Whether you are developing advanced oral vascular health capsules or premium targeted eye creams, prioritizing the purity and structural integrity of your raw materials is key to formulation success.

About us

Private Label design, fast delivery, USA Warehouse, European Warehouse, capsules factory,Softgels factory,tablets factory, pills factory, Gummies factory, Liquid Drops factory,Gum factory,solid beverage factory, customized factory, capsules manufacturer,Softgels manufacturer, tablets manufacturer, pills manufacturer, Gummies manufacturer, Liquid Drops manufacturer,Gum manufacturer,solid beverage manufacturer, customized manufacturer.

Our advantage

We possess extensive experience, handling every step from sourcing each ingredient in the formulation to post-filling inspection, all at the most competitive prices and with the fastest delivery times.

InterlGroup owns factory, Main Product Foods additives, Nutritional supplements, Healthcare Products(capsules,Softgels,tablets,Gummies,Liquid Drops,Gum,solid beverage and other customized products), plant extracts.

Support OEM&ODM service，Design label packaging, Overseas in stock, Fast customization, Drop Shipping.

Intergroup is supplying OEM service for the Well-known brands Reson and Ausreson. 

Alibaba International Station No.1 supplier,  Alibaba International Station Number 1, Alibaba International Station Number one.