Econazole nitrate Raw materials powder supplier

CAS:68797-31-9

MF:C18H16Cl3N3O4

MW:444.7

EINECS:272-295-6

Specification: 99% min Econazole nitrate powder

Sample:Econazole nitrate powder Avaliable

Packaging:1kg/bag, 25kg/drum

Brand: Ausreson

Appearance:white powder

Storage: Store at -20°C

Shelf Life: 2 Years

Test Method: HPLC

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Econazole nitrate powder of Usage and Synthesis.

Econazole nitrate is a western medicine, commonly used preparations are solution, suppository, spray, cream and so on. It is an antifungal drug. For the treatment of cutaneous candidiasis; It can also be used to treat tinea corporis, jock itch, tinea pedis, tinea versicolor, and for candida vulvovaginosis.

Body ringworm: neck, waist, abdomen, trunk and limbs, papules or small blisters and other symptoms, you can consider using this product to relieve, can inhibit fungus.

Jock itch: Circular, papular and other manifestations of skin lesions in the groin, perineum, perianal and buttocks, feeling itching, can consider using this product to relieve, can play an antifungal role.

Tinea pedis: When peeling, blisters, pruritus and other skin symptoms occur between toes, sole, heel and lateral edge of foot, you can consider using this product to treat it and help relieve symptoms.

Tinea picrosus: Malazzia encroaching on the stratum corneum of the skin causes skin fungal infection, which can lead to skin redness, itching and desquamation, etc., at this time can be treated with this product, which can play an antibacterial role.

Candidiasis: includes treatment of cutaneous candidiasis as well as candidiasis vulvovaginosis, which can act as an antifungal agent.

Uses of Econazole nitrate.

For the treatment of cutaneous candidiasis; It can also be used to treat tinea corporis, tinea handi, tinea corporis, tinea pedis, tinea versicolor, etc.

Pharmacological action of Econazole nitrate.

Econazole nitrate is a pyrrole antifungal drug and a dechloroderivative of miconazole. It has antibacterial action against Candida, Pigmentum, Coccidioides, histoplasmosis, Sporotrichophyton, etc. It also has antibacterial activity against trichophyton trichophyton. It has a poor effect on Aspergillus, Sporotrichia Schenckii, some melanosporaceae, Mucor, etc. By interfering with the activity of cytochrome P450, it inhibits the biosynthesis of ergosterol, the main steroid of fungal cell membrane, damages fungal cell membrane and changes its permeability, resulting in the leakage of important intracellular substances. It can inhibit the biosynthesis of triacylglycerol and phospholipids of fungi, inhibit the activity of oxidase and peroxidase, and cause intracellular hydrogen peroxide accumulation leading to cell submicrostructure degeneration and cell necrosis. Candida albicans can inhibit the process of its transformation from spore to aggressive mycelium. It is suitable for tinea handi, tinea pedis, tinea jock, tinea corporis, tinea versicolor and candidiasis of skin.