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Pharmaceutical 10mg Prasugrel raw materials Powder Prasugrel
Product Overview:
Pratgrel, a thienopyridine antiplatelet drug developed by Eli Lilly and Japanese drugmaker DaiichiSankyo, is a precursor drug that is metabolized by cytochrome P450 in the liver to form an active molecule that binds to the platelet P2Y12 receptor to exert anti-platelet aggregation activity. Clinical studies have proved that the 60 mg dose has a better anticoagulant effect than the 300 mg standard dose of clopidogrel and the 600 mg increased dose, which can reduce the combined risk of heart attack, stroke and death from heart disease by 20%, and the effect is fast and good, with good drug resistance and bioavailability, and the toxicity is also low.
Pharmaceutical 10mg Prasugrel raw materials Powder Prasugrel Attributes
CAS:150322-43-3
MF:C20H20FNO3S
MW:373.44
EINECS:801-962-1
Specification: 99% min Prasugrel powder
Sample:Prasugrel Powder Avaliable
Packaging:1kg/bag, 25kg/drum
Brand: Ausreson
Appearance:white powder
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Pharmaceutical 10mg Prasugrel raw materials Powder Prasugrel Details
Prasugrel Usage and Synthesis.
Pragrel also has a stronger performance than clopidogrel in interventional surgery for stable angina pectoris and acute coronary syndrome, but the stronger the antiplatelet effect is, the more likely it is to cause bleeding. The key question now is how we can identify patients at high risk of thrombosis and how we can identify those at high risk of bleeding in the clinic, so that pragrel and clopidogrel can be used differently in the two high-risk groups, both to reduce coronary thrombosis and avoid major bleeding.
Prasugrel vs. Alternatives
| Drug | Onset | Bleeding Risk | Best For |
|---|---|---|---|
| Prasugrel | 30 min | High | ACS with PCI |
| Clopidogrel | 6+ hrs | Moderate | Stroke history |
| Ticagrelor | 30 min | High | NSTEMI |
In vitro study of Prasugrel.
Prasugrel, a novel orally active thiophenyl pyridinium, has faster, higher and more reliable platelet aggregation inhibition than clopidogrel, indicating that it is metabolized in vivo as an active metabolite with selective P2Y(12) antagonistic activity.
FAQs
Q: How long must I take prasugrel?
A: Typically 12 months post-stent – DO NOT STOP without doctor approval.
Q: What if I miss a dose?
A: Take ASAP if <12 hrs late; otherwise skip. Never double dose.
Q: Can I take NSAIDs?
A: Avoid – increases bleeding risk (ibuprofen, aspirin >100mg).
Q: Why is prasugrel stronger?
A: More consistent CYP enzyme metabolism vs. clopidogrel.
Q: Signs of bleeding emergency?
A: Black stools, vomiting blood, severe headache → seek ER care.
Product Safety and Compliance Details
Safe use
As the Food and Drug Administration (FDA) advises, dietary supplements can support your overall health but may also have powerful effects on the body. It’s important to read labels carefully, exercise caution, and consult your healthcare professional before taking any supplement. Side effects are more likely if supplements are taken in high doses, as substitutes for prescribed medications, or in combination with multiple supplements. If you experience severe side effects, discontinue use immediately and seek medical attention.
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