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Pharmaceutical Ingredients mupirocin 2 ointment raw material Powder
Product Overview:
Mupirocin (also known as pseudomonosporic acid A) is an ideal anti-bacterial preparation for the skin surface, which was introduced to the market by GlaxoSmithKline in 1985 under the trade name Bactroban. The United States FDA approved the drug for use in the United States in 1987, and China approved the production and sale of the drug by SmithKline Pharmaceutical in 1993. Mupirocin is mainly used for the prevention and treatment of skin bacterial infections caused by gram-positive bacteria.
Pharmaceutical Ingredients mupirocin 2 ointment raw material Powder Attributes
CAS:12650-69-0
MF:C26H44O9
MW:500.62
EINECS:603-145-3
Specification: 99% min Mupirocin Powder
Sample:Mupirocin Powder Avaliable
Packaging:1kg/bag, 25kg/drum
Brand: Ausreson
Appearance:white powder
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Pharmaceutical Ingredients mupirocin 2 ointment raw material Powder Details
Mupirocin powder Usage and Synthesis.
Mupirocin is mainly used for the prevention and treatment of skin bacterial infections caused by gram-positive coccus, such as impetigo, furuncle, folliculitis and other primary skin infections, and eczema co-infection, ulcer co-infection, trauma co-infection and other secondary skin infections. The main mechanism of mupirocin's antibacterial action is to inhibit protein synthesis in bacteria.
Dosage and Administration
For external use: Apply to the affected area, bandage or cover with dressing if necessary, 2 to 3 times a day, 5 days as a course of treatment. Repeat the course of treatment if necessary.
mupirocin vs neosporin.
| Feature | Mupirocin (Bactroban) | Neosporin |
|---|---|---|
| Type | Prescription-only | OTC |
| Active Ingredient | Mupirocin | Neomycin + Polymyxin B + Bacitracin |
| Best For | Staph/MRSA infections, impetigo | Minor cuts, scrapes, burns |
| MRSA Coverage | Yes | No |
| Healing Speed | 2-3 days (infections) | Prevents infection in minor wounds |
| Side Effects | Mild burning/itching | Higher allergy risk (neomycin) |
| Cost | $$$(insurance may cover) | $(affordable) |
Uses of Mupirocin.
Topical antibiotics. By reversibly binding to isoleucine transfer RNA synthetase, isoleucine is prevented from entering the human body, thus halting the synthesis of all proteins containing isoleucine in the cell. For acute primary bacterial skin infections, such as folliculitis and impetigo. It is generally used for skin disease inflammation, eczema, etc., to make Mupirocin ointment on the market.
FAQ.
Q: Is mupirocin better than oral antibiotics?
A: For localized skin infections (impetigo, small wounds), yes! Fewer side effects than pills.
Q: Can mupirocin treat fungal infections?
A: ❌ No—it’s antibacterial only (use clotrimazole for fungus).
Q: How quickly does it work?
A: Improves symptoms in 2-3 days; finish full course (5-10 days) to prevent resistance.
Q: Can I use expired mupirocin?
A: ❌ No—effectiveness declines after expiration.
Q: Is mupirocin safe for babies?
A: ✅ Yes, for ages 2+ (consult pediatrician first).
Pharmacological action
mupirocin 2 ointment is a topical antibiotic, a substance produced by the culture fluid of Pseudomonas fluorescens, namely Pseudomonas A. Its antibacterial effect is mainly through reversible binding to isoleucine transfer RNA synthetase, preventing isoleucine from penetrating, and stopping the synthesis of isoleucine-containing proteins in cells to kill or inhibit bacteria.
This drug shows an antibacterial effect at very low concentrations and a bactericidal effect at high concentrations. This drug is highly sensitive to various Gram-positive cocci related to skin infections, especially Staphylococci and Streptococci, and is also effective against drug-resistant Staphylococcus aureus; it has a certain antibacterial effect on certain Gram-negative bacteria such as Escherichia coli, Haemophilus influenzae and Neisseria gonorrhoeae; it is not sensitive to most anaerobic bacteria and normal skin flora. The incidence of in vitro drug-resistant variants is very low.
Product Methods of Mupirocin.
A class of substances produced by Pseudomonas fluorescens, including pseudomonas acid A, B, C, D, of which mupirocin is the main metabolite of pseudomonas acid A.
