100mg Doxycycline Hyclate Powder High-purity API

CAS:24390-14-5

MF:C24H31ClN2O9

MW:526.97

EINECS:2017-001-1

Specification: 99% min Doxycycline Hyclate Powder

Sample:Doxycycline Hyclate Powder Avaliable

Packaging:1kg/bag, 25kg/drum

MOQ:1KG

Brand: Ausreson

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Doxycycline Hyclate Powder Usage and Synthesis.

Doxycycline hydrochloride is a semi-synthetic tetracycline antibiotic that penetrates cell membranes and binds to the 30S ribosomal subunit, interfering with tRNA/mRNA interactions and ultimately inhibiting protein synthesis.

As a broad-spectrum antibiotic and bacteriostatic agent, this antibiotic is very resistant primarily to bacteria that cause respiratory tract infections including Mycoplasma pneumoniae and Haemophilus influenzae.

It also treats infections caused by Chlamydia, Rickettsia, and certain spirochetes and has antiprotozoal and deworming properties.

Uses and functions of Doxycycline Hyclate.

Doxycycline Hydrochloride is commonly used for the treatment of small animal infections caused by a number of different microorganisms, including Borrelia, Leptospira, Rickettsia, Chlamydia, Mycoplasma, Bartonella and Bordetella.

what is doxycycline hyclate 100 mg used for

1. For bacterial infections: "I have inflammation, redness, swelling, and pain somewhere on my body."

• Respiratory infections: These include acute exacerbations of chronic bronchitis and pneumonia. When you have a persistent cough, pus-producing sputum, and chest pain, it may be used to clear specific bacteria from your lungs.
• Skin and soft tissue infections: These include severe acne, cellulitis, and wound infections. It penetrates deep into the skin tissue to fight the bacteria that cause redness, swelling, and pus.
• Urogenital infections: These include non-gonococcal urethritis and chlamydia. It is a standard treatment for these specific pathogens.
• Eye infections: It is used to treat certain types of conjunctivitis.

2. For parasitic infections and complex inflammatory conditions: "My problem keeps coming back for unknown reasons."

• Rosacea: For rosacea with papules and pustules, low-dose doxycycline is widely used for its anti-inflammatory properties. Its primary function here is not to kill bacteria, but to suppress the skin's excessive inflammatory response, thereby calming the redness, swelling, and breakouts.
• Periodontitis: Also utilizing its anti-inflammatory properties, it can be used as an adjunctive treatment for active, aggressive periodontal disease caused by specific bacteria.

3. Targeting travel and outdoor risks: "I feel unwell after traveling or engaging in outdoor activities."

• Traveler's diarrhea: It is used to treat severe diarrhea caused by specific bacteria.
• Lyme disease: It is the preferred early treatment for erythema migrans (bull's eye rash) after a tick bite.
• Malaria prevention: It can be used as a preventative medication when traveling to malaria-endemic areas (note: prevention, not treatment).

Pharmacological Effect of Doxycycline Hyclate.

Tetracycline antibiotics are bacteriostatic antibiotics that inhibit protein synthesis by reversibly binding to the 30S ribosomal subunit of sensitive bacteria and thereby preventing their binding to aminoacyl transfer RNA.Chemicalbook.It has also been suggested that tetracyclines can reversibly bind to the 50S subunit and alter the permeability of sensitive bacterial cell membranes, and can also inhibit protein synthesis in mammalian cells at high concentrations.

In vivo studies of  Bulk Doxycycline Hyclate Powder.

Doxycyclinehyclate is an effective treatment for acute E. canis infections in puppies.

Doxycyclinehyclate (5 mg/kg, orally) decreased collagenase activity in rabbit cornea. Doxycyclinehyclate (5 mg/kg, orally) promoted corneal epidermal cell regeneration in a rabbit alkali burn model, a result that may be attributed to the drug's inhibition of excess collagenase activity.

Doxycyclinehyclate would have prevented 43% of the mice treated orally, in contrast to the extended-release doxycyclinehyclate, which completely protects mice from infections and pathologies caused by infections.

Doxycyclinehyclate has a bioavailability of 70%, a Cmin of 1 mg/L, a Cmax of 2.3 mg/L and a half-life of 7 hours in calves with immature rumen function.