Bulk 95% purity Chondroitin sulfate raw material supplier

CAS: 3416-24-8 

MF: C6H13NO5

MW:  179.17

EINECS:  222-311-2

Specification​: 99% min Glucosamine Powder

Packaging: 1kg/bag. 25kg/bag

MOQ: 1 KG

Brand: Ausreson

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Chondroitin Sulfate Powder Raw Material Powder Usage and Synthesis

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Applications and Product Innovation

The application of chondroitin sulfate has expanded from traditional medicine to diversified markets. According to segmented data, its main applications include pharmaceuticals, animal nutrition, and cosmetics.

In the joint health supplement market, innovation is key to growth. There is a clear trend towards formula upgrades, shifting from traditional single-ingredient formulations to compound formulas such as "glucosamine + chondroitin + collagen + hyaluronic acid + vitamin D + natural antioxidants."

This innovation not only enhances product efficacy but also creates richer product portfolio opportunities for raw material suppliers.

Improving bioavailability is an important direction for product innovation. By adopting microencapsulation sustained-release technology, the release period of active ingredients in the body can be extended, enhancing the effect.

Meanwhile, a variety of dosage forms, such as gummies, instant powders, and dairy-fortified formulations, provide consumers with more choices and improve usage adherence.

Scientific Basis of its Mechanism of Action:

The arthroprotective effect of chondroitin sulfate has a solid scientific basis. As an important component of articular cartilage, it can effectively reduce the protein production of inflammatory cytokines, iNOS, and MMPs.

By inhibiting the inflammatory response, chondroitin sulfate reduces damage to chondrocytes.

In clinical trials, scientists have found that chondroitin sulfate can reduce the susceptibility of chondrocytes to single nucleotide polymorphism-induced apoptosis. Simultaneously, it can promote cartilage matrix synthesis, maintain the proteoglycan content of articular cartilage, and stimulate chondrocytes to synthesize type II collagen and proteoglycans.

These mechanisms work together to delay the degenerative process of articular cartilage. For patients in the early stages of osteoarthritis, oral chondroitin sulfate preparations can effectively relieve symptoms, reduce swelling in inflamed areas, lower matrix metalloproteinase-9 levels, and reduce OA-induced cartilage damage.

Uses and functions of Chondroitin Sulfate Powder

1. Chondroitin sulphate has been used as a health food or health care drug for a long time in the prevention and treatment of coronary heart disease, angina pectoris, myocardial infarction, coronary atherosclerosis, myocardial ischemia and other diseases, with no obvious toxic side effects, and it can significantly reduce the morbidity and mortality rate of patients with coronary heart disease.

Long-term clinical application found in the arteries and veins wall deposits of fat and other lipids can be effectively removed or reduced, can significantly reduce plasma cholesterol, thus preventing the formation of atherosclerosis.

• 2. Chondroitin sulphate is used in the treatment of neuralgia, neurogenic migraine, arthralgia, arthritis and scapular joint pain, pain after abdominal surgery.
• 3. It is effective in preventing and treating the hearing disorder caused by streptozotocin as well as the hearing difficulty and tinnitus caused by various noises.
• 4. It has auxiliary therapeutic effect on chronic nephritis, chronic hepatitis, keratitis and corneal ulcer.
• 5. In recent years, it has been reported that chondroitin in shark cartilage has anti-tumour effect. In addition, chondroitin sulfate is also used in cosmetics and wound healing agents.
• 6. Chondroitin sulphate is also used in eye drops.

Bioactive pharmacological effects of Chondroitin Sulfate Powder Raw

Chondroitin sulphate is widely found in human and animal cartilage tissues. Its medicinal preparation mainly contains chondroitin sulphate A and chondroitin sulphate C two isomers, the cartilage of different species, age and other animals in the chondroitin sulphate content is different. Its pharmacological effects are shown as:

• 1, chondroitin sulfate can remove lipids and lipoproteins in the blood of the body, remove cholesterol from the blood vessels around the heart, prevent and control atherosclerosis, and increase the conversion rate of lipids and fatty acids in the cells.
• 2, chondroitin sulfate can effectively prevent and control coronary heart disease. For experimental atherosclerosis model with anti-atherosclerosis and anti-atherogenic plaque formation; increase atherosclerosis coronary artery staging or collateral circulation, and can accelerate experimental coronary atherosclerosis or embolism caused by myocardial necrosis or degeneration of healing, regeneration and repair.
• 3, can increase the cellular messenger ribonucleic acid (mRNA) and deoxyribonucleic acid (DNA) biosynthesis as well as has the effect of promoting cell metabolism.
• 4, low anticoagulant activity. Chondroitin sulfate has a mild anticoagulant effect, each lmg of chondroitin sulfate A is equivalent to 0.45U heparin anticoagulant activity.
• This anticoagulant activity does not depend on antithrombin III and play a role, it can play an anticoagulant activity through the fibrinogen system.
• 5, chondroitin sulfate also has anti-inflammatory, accelerate wound healing and anti-tumour effects.
• Production method of Chondroitin Sulfate Powder

Frequently Asked Questions

What are the main sources of chondroitin sulfate?

There are three main sources: pork cartilage, seafood (especially shark bone), and bovine cartilage. Chondroitin sulfate from different sources differs slightly in molecular structure and efficacy; the target market and the characteristics of the final product should be considered when choosing.

What are the recommended storage conditions for chondroitin sulfate?

To ensure product quality and extend shelf life, it is recommended to store it at -25°C to -15°C. Under these conditions, chondroitin sulfate can typically maintain its stability and efficacy for 3 years.

What are the main growth drivers of the chondroitin sulfate market?

The three main growth drivers include: the rising prevalence of osteoarthritis globally, particularly among the elderly; increasing consumer interest in nutritional supplements; and the accelerating trend of global population aging. These factors have collectively driven the expansion of the joint health products market.

How does chondroitin sulfate work to support joint health?

Primarily by reducing inflammatory mediators and apoptosis processes, decreasing the production of inflammatory cytokines, iNOS, and MMPs. Simultaneously, it can promote cartilage matrix synthesis, maintain the proteoglycan content of articular cartilage, and stimulate chondrocytes to synthesize type II collagen and proteoglycans.

What are the typical application areas of chondroitin sulfate raw materials?

It is mainly used in three major areas: pharmaceuticals (such as joint health drugs), animal nutrition (pet joint health supplements), and cosmetics (anti-aging skincare products). In addition, it is also widely used in joint health dietary supplements.

Our Strengths

Henrikang possesses the capability to manufacture any capsule formulation. From sourcing every ingredient in the formula to post-filling inspection, we undertake the entire process at optimal pricing and with the swiftest delivery times.

With extensive experience, we can assist you in developing new products for your target audience or discuss how to scale up production efficiently. As your partner, we are committed to achieving long-term success in capsule manufacturing.

As a leading Chinese OEM manufacturer for nutritional supplement ingredients and branded products, we hold certifications including ISO 22000, ISO 9001, HACCP, GMP, Halal, CE, CE-ROHS, Kosher, SGS, Intertek, Eurofins, and GMP. Our facility has successfully undergone US FDA inspection and registration.

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