Wholesale Food Grade Vitamin a Palmitate Powder

CAS: 79-81-2

MF: C36H60O2

MW: 524.86

EINECS: 201-228-5

Specification: 99% min Vitamin A Palmitate Powder

Sample: Vitamin A Palmitate Powder Avaliable

Packaging:1kg/bag, 25kg/drum

Brand: Ausreson

MOQ: 1 kg

Appearance: Light Yellow to Yellow Oil

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Vitamin A Palmitate Powder Usage and Synthesis.

Vitamin A Palmitate Ophthalmic Gel (Zync) is used clinically, and in terms of experience with its use, it is primarily directed at repairing the function of cuprocytes and reversing cellular keratinisation.

Conjunctival cup cells are an important part of the conjunctival epithelium and their main function is to secrete mucin to protect and lubricate the ocular surface. Conjunctival inflammation caused by allergic conjunctivitis, dry syndrome, burns, etc., can damage the cup cells and lead to abnormal mucin layer.

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Uses and functions of Vitamin A Palmitate.

Vitamins

It can be absorbed transdermally, anti-keratinisation, stimulate the growth of collagen and elastin, increase the thickness of epidermis and dermis. Enhances skin elasticity, effectively eliminates wrinkles, promotes skin renewal and maintains skin vitality. Used in eye cream, moisturiser, repair cream, shampoo, conditioner, etc.

Core Applications:

Retinyl palmitate has a wide range of applications, from clinical treatment to daily health maintenance. Here are some of its main applications:

In skin and eye health, retinyl palmitate can stimulate keratinocytes and endothelial cells, activate dermal fibroblasts to synthesize extracellular matrix proteins, and possesses strong antioxidant properties.

These effects thicken the epidermis, increase skin mechanical strength and hydration, and improve angiogenesis. In ophthalmology, retinyl palmitate ophthalmic gels are used as an adjunct treatment for dry eye caused by various factors.

In immune regulation, scientific research has shown its potential value in specific diseases. For example, retinyl palmitate supplementation can regulate the expression of immune system-related genes in peripheral blood mononuclear cells of patients with multiple sclerosis (MS).

One study found that retinyl palmitate supplementation significantly reduced the expression of T-bet and interferon-γ genes in patients with multiple sclerosis.

There are also examples of its application in the clinical treatment of specific diseases. A randomized, double-blind trial found that oral retinyl palmitate significantly reduced rectal symptoms in patients with radiation proctitis, which researchers believe may be attributed to its wound-healing effect.

Pharmacological Effect of Vitamin A Palmitate.

Due to its long retention time, it is suitable for use as a tear replacement in the treatment of tear deficiency and "dry eye", which is caused by tear film instability and subsequent high secretion due to low tear quality.

The higher viscosity enhances the protective effect of the gel through physical lubrication. The addition of vitamin A enhances the therapeutic effect by eliminating the symptoms of corneal epithelial dehydration.

Vitamin A (retinol) is necessary for normal epithelial cell differentiation, and retinol deficiency leads to a decrease in cup cells, epithelial cell atrophy and conjunctival basal cell proliferation.

How to Use Safely:

After understanding the scientific value of vitamin A palmitate, it's even more important to know how to use it safely and effectively. This includes choosing the right dosage form, adhering to the appropriate dosage, and understanding necessary precautions.

Dietary supplements are the most common form of application. For example, Carlson brand vitamin A supplements provide 15,000 IU (equivalent to 4,500 micrograms of retinol active equivalent) in palmitate form.

According to the Nordic Nutrition Recommendations (2023), the recommended daily intake for adult men is 800 RE (retinol equivalents), and for women, it is 700 RE.

Special precautions apply to certain populations. Pregnant women or women planning to become pregnant should avoid using high doses of vitamin A supplements, as daily intake exceeding 10,000 IU of vitamin A may lead to birth defects.

Vitamin A supplements are prohibited for use by pregnant women, breastfeeding patients, and patients with allergies to these medications.

When using vitamin A palmitate eye gel, specific usage instructions must be followed. The usual adult dose is 1 drop three times daily or 1 drop every hour. Occasionally, a brief burning sensation, eyelid adhesion, or blurred vision may occur after application.

In vitro studies of Bulk Vitamin A Palmitate Powder.

Microencapsulation of vitamin A palmitate by gelatin-gum arabic complex is a promising method for converting oily vitamins into solid powders, thus facilitating handling and easy preparation of blends

Frequently Asked Questions about Vitamin A Palmitate

Q: What is the difference between Vitamin A palmitate and regular Vitamin A?

Vitamin A palmitate is a stable form of Vitamin A, formed by esterifying retinol with palmitate. It is more resistant to heat, light, and oxidation than pure retinol, and therefore has a wider range of applications in food, supplements, and skincare products.

Q: What are the specific benefits of Vitamin A palmitate for the skin?

It improves skin health by stimulating epidermal thickening, enhancing skin mechanical strength, increasing moisture content, and promoting angiogenesis. It is commonly used in skincare formulations for anti-aging and improving skin texture.

Q: What is the recommended daily intake? Are there differences among different populations?

According to the Nordic Nutrition Recommendations (2023), the recommended daily intake for adult men is 800 RE (retinol equivalents), and for women, it is 700 RE. Pregnant or breastfeeding women should use it under the guidance of a doctor, as high doses may cause fetal development problems.

Q: What precautions should be taken when using Vitamin A Palmitate eye gel?

A temporary burning sensation or blurred vision may occur after use. Driving or operating machinery should only be attempted after vision has returned to normal. Contact lens wearers should remove their lenses and wait 30 minutes before re-wearing.

Q: What side effects or risks should be noted?

Long-term use in high doses may lead to hypervitaminosis A, manifesting as nausea, vomiting, skin problems, and even liver damage. Acute toxicity may occur with a single ingestion of 25,000 IU/kg or higher.

Q: What medications or supplements can vitamin A palmitate interact with?

Currently, it is recommended to use other eye drops 5-10 minutes before using eye gels, and they should be used last. Data on interactions between oral supplements and other medications are limited; it is recommended to consult a healthcare professional before use.

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