bulk Phillyrin powder 98% Forsythia Suspensa Extract supplier

CAS:  487-41-2

MF: C27H34O11

MW: 534.55

Specification​: 99% min Phillyrin powder Avaliable

Packaging: 1kg/bag. 25kg/bag

Brand: Ausreson

MOQ: 1 kg

Appearance: brown Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Phillyrin Raw Material Powder Usage and Synthesis

Phillyrin Raw Material Factory Supply Phillyrin Nutritional Supplement Phillyrin Powder Raw Material, High Quality Phillyrin Powder Purity 99% Phillyrin Powder Raw Material is has the effect of clearing away heat, detoxifying, dispersing knots and draining pus, and is mainly used in the treatment of warmth and fever, sores, scrofula, dengue poisoning, banana rash, and influenza.

Manufactory Supply Phillyrin Powder Raw Material, High Purity Phillyrin Powder Nutritional Supplement Phillyrin Raw Powder, High Quality Phillyrin Powder.

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Core Bioactivities and Mechanisms of Action of Phillyrin

Antibacterial and Anti-inflammatory Properties

One of the most significant effects of Phillyrin is its antibacterial and anti-inflammatory properties. Studies have shown that it can regulate the activity of key enzymes in vivo. Specifically, Phillyrin has a potential inducing effect on CYP1A2 and CYP2D1 enzymes in rats, but does not affect the activities of CYP2C11 and CYP3A1/2. This selective regulation is crucial for understanding its metabolism and interactions in vivo.

Antiviral Activity

Of particular note is the antiviral activity of Phillyrin against influenza A virus. Animal experimental data show that administration at a dose of 20 mg/kg daily for 3 days significantly prolonged the mean survival time of mice infected with influenza virus, reduced viral load and interleukin-6 (IL-6) levels in the lungs, and alleviated lung tissue damage.

Metabolic Regulation and Protection

In terms of metabolic health, Phillyrin can prevent fat accumulation in HepG2 cells of the liver by activating the LKB1/AMPK signaling pathway. This mechanism is achieved by inhibiting the expression of key proteins related to lipid synthesis, SREBP-1c and fatty acid synthase (FAS), demonstrating its potential application value in metabolic syndrome and related diseases.

Bioactive pharmacological effects of Phillyrin Raw Powder

White crystalline powder, easily soluble in benzene, ether, chloroform, from forsythia Forsythiasuspense, Rehmanniaglutinosa, Admiralty Fruit.

UsesForsythiasuspense has the effect of clearing away heat, detoxifying, dispersing knots and draining pus, and is mainly used in the treatment of warmth and fever, sores, scrofula, dengtoxin, banana rashes, and influenza.

Production method of Phillyrin Powder

• Used for content determination/identification/pharmacological experiments.
• Pharmacological effects:Lowering blood lipids, antioxidant effects.

Frequently Asked Questions

Is Phillyrin safe for humans?

Currently available research data primarily focuses on preclinical studies (in vitro and animal experiments). Its safety and efficacy in humans have not been fully evaluated, therefore it cannot be directly used in humans. Any potential future clinical application must undergo rigorous and complete clinical trials.

What is the relationship between Phillyrin and Forsythin?

They are two different names for the same compound. Phillyrin is the more commonly used name, and Forsythin is its alternative name; both refer to forsythoside extracted from Forsythia suspensa.

How should I store Phillyrin powder to maintain its activity?

To maximize its bioactivity, Phillyrin powder should be stored in a sealed, light-protected, and dry place. The recommended long-term storage temperature is -20°C (shelf life 3 years). For short-term or frequent use, it can be stored at 4°C (shelf life 2 years). Once prepared as a solution, its stability decreases, requiring storage at ultra-low temperatures as recommended above, and repeated freeze-thaw cycles should be avoided.

What precautions should be taken when dissolving Phillyrin in experiments?

DMSO is the preferred solvent. The key is to ensure complete dissolution and accurate concentration. Because DMSO is hygroscopic, which reduces its dissolving power, always use freshly opened DMSO or properly stored in a moisture-proof environment. For cases where dissolution is difficult, a short-duration, low-frequency ultrasonic treatment can be used during dissolution.

Оптовый поставщик порошка Филлирина 98%, экстракт Forsythia Suspensa
Fournisseur en gros de poudre de Phillyrine 98%, extrait de Forsythia Suspensa
Großhandelslieferant für Phillyrin-Pulver 98%, Forsythia Suspensa-Extrakt
Proveedor al por mayor de polvo de Phillyrin 98%, extracto de Forsythia Suspensa
Fornecedor atacadista de pó de Phillyrin 98%, extrato de Forsythia Suspensa