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  • high purity Silodosin 4mg 8mg Raw Materials Powder supplier

    • high purity Silodosin 4mg 8mg Raw Materials Powder supplier
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    Product Overview:

    Silodoxin is an alpha-adrenergic receptor antagonist invented by Kissei Pharmaceutical Company in Japan, which has a very good effect on the treatment of urinary disorders associated with benign prostatic hyperplasia. The selective effect on urethra was 12 and 7.5 times higher than prazosin and Tamsulosin, respectively, and could significantly inhibit the prostate contraction induced by norepinephrine. It can inhibit bladder hyperactivity in a dose-dependent manner and increase the pressure threshold of bladder contraction in benign prostatic hypertrophy rats. These data suggest that cilodoxin, in addition to improving bladder function, may also be effective in relieving symptoms associated with benign prostatic hypertrophy.

    high purity Silodosin 4mg 8mg Raw Materials Powder supplier Attributes

    Silodosin Raw Materials Powder

    CAS:160970-54-7

    MF:C25H32F3N3O4

    Silodosin

    MW:495.53

    EINECS:814-909-2

    Specification​: 99% min Silodosin Powder

    Sample:Silodosin Powder Avaliable

    Packaging:1kg/bag, 25kg/drum

    Brand: Ausreson

    Appearance:white powder

    Storage: Cool Dry Place

    Shelf Life: 2 Years

    Test Method: HPLC

    high purity Silodosin 4mg 8mg Raw Materials Powder supplier Details

     

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    Silodosin Usage and Function.

    Compared to its peers Prazosin and Tamsulosin, silodoxin is highly selective towards α1A-receptors located in the prostate and bladder neck, while its affinity for α1B- and α1D- receptors is not significant. It blocks the alpha1A-receptor at this site, relaxes smooth muscle, and leads to improved urine flow and reduced BPH symptoms.Поставщик сырья – высокочищенный силодозин (4 мг/8 мг) в форме порошка

    Silodoxin binds more selectively to the α1A-receptor than to the cardiovasculary-associated α1b-receptor, maximizing activity to the target organ while minimizing potential effects on blood pressure.Lieferant von hochreinem Silodosin (4 mg/8 mg) Rohstoffpulver

    Hot selling Silodosin Powder – A prescription alpha-1 blocker used to manage benign prostatic hyperplasia (BPH) symptoms. For professional use only. Always consult a healthcare provider.Proveedor de materia prima en polvo de silodosina de alta pureza (4 mg/8 mg)

    Silodosin Powder

    Uses of Silodosin.

    The α1-adrenergic receptor is a G protein-coupled receptor: by binding to its natural ligands norepinephrine and epinephrine, it activates phospholipase C and downstream signaling molecules, including inositol triphosphate and diglycerol. Eventually, intracellular calcium levels increase, so smooth muscle contracts.Fornecedor de matéria-prima em pó de silodosina de alta pureza (4 mg/8 mg)

    Silodosin is an alpha1-adrenergic receptor antagonist with the highest selectivity for the alpha1a-adrenergic receptor subtype. By blocking the α1a-adrenergic receptor signaling pathway, silodoxin promotes relaxation of the prostate and urethral smooth muscle, thereby improving lower urinary tract symptoms such as urination. Silodoxin also targets the afferent nerves in the bladder, relieving symptoms of bladder overactivity and storage.Fournisseur de poudre de silodosine (4 mg/8 mg) de haute pureté pour matières premières

    Key Benefits of Silodosin Powder

     High Purity (≥99%) – Suitable for pharmaceutical formulations

     Selective Action – Targets α1A-receptors with minimal blood pressure effects

     Improved Bioavailability – Optimized for fast absorption

     BPH Symptom Relief – Reduces urinary retention, frequency, and urgency

    Silodosin

    FAQs About Silodosin Powder

    Q: What is the recommended dosage for Silodosin?

    A: Typically 4-8 mg per day, but always follow medical guidance.

    Q: Are there any side effects?

    A: Common side effects may include dizziness, retrograde ejaculation, or nasal congestion.

    Q: Is Silodosin safe for long-term use?

    A: Yes, clinical studies support its safety for chronic BPH management.

    Q: Do you offer sample testing?

    A: Yes, we provide small samples for quality verification.

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