Pancreatin Raw Materials Powder Pancreatin

CAS:8049-47-6

MF:/

MW:/

EINECS:232-468-9

Specification: 99% min Pancreatin

Sample:Pancreatin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Pancreatin Powder Usage and Synthesis.

Pancreatic enzymes hydrolyze fats, starches and proteins. After oral administration the capsule dissolves in the stomach, releasing hundreds of pancreatic enzyme particles with enteric coating. It can avoid inactivation in the stomach and mixes well with food in the stomach and enters the duodenum synchronously with food. In the proximal part of duodenum, the particles immediately disintegrate, releasing more than 80% of the activity within 130min, ensuring the digestion and absorption of nutrients.

Pancreatic enzymes are used for the replacement therapy of pancreatic exocrine insufficiency caused by various reasons (e.g. cystic fibrosis, chronic pancreatitis, post-pancreatectomy, post-gastrectomy, tumor-induced obstruction of pancreatic or common bile ducts, chronic inflammatory pain of pancreas, elderly people, gastrointestinal, hepatic and gallbladder diseases).

This product contains trypsin, amylase and other digestive enzymes, can digest protein, starch. It can digest protein and starch. It also has a digestive effect on fat. It is used for pancreatic dysfunction, diabetic patients with dyspepsia and so on. This product in neutral or slightly alkaline when the effectiveness of the best, so more with sodium bicarbonate.

Uses of Pancreatin.

Pancreatic enzyme can be used as a digestive aid; it is mainly used for dyspepsia, loss of appetite and dyspepsia in patients with digestive disorders due to pancreatic diseases and uropathy.

It is mostly taken with sodium bicarbonate or made into enteric-coated tablets; it should not be crunched when taken orally to avoid being destroyed by gastric acid, and should not be paired with acidic drugs. It can cause diarrhea when as large as possible. Vomiting. Occasionally sneezing. Tear, rash and other allergic symptoms should be discontinued.

Used in biochemical studies and clinically as a digestive aid for dyspepsia, loss of appetite, digestive disorders caused by pancreatic diseases and diabetic patients with dyspepsia.

It is used as a digestive aid for dyspepsia caused by lack of ductal pancreatic fluid. It is also used in leather industry and textile printing and dyeing, mainly for enzymatic hair removal.

Pharmacological effect of Pancreatin.

Taken with an equal amount of sodium bicarbonate can enhance the efficacy. Cimetidine inhibits gastric acid secretion and increases pH in the stomach and duodenum, so it prevents inactivation of pancreatic enzymes and enhances the efficacy of oral pancreatic enzymes. Because all Hz receptor antagonists decrease intragastric acidity, it is hypothesized that ranitidine, famotidine, and nizatidine also have this interaction with pancreatic enzymes.

Reduction of pancreatic enzyme dose may be required when combined. The activity of this drug is weakened in acidic solutions or even inactivated by splitting, so it is contraindicated to take it with acidic drugs. When this drug is combined with acarbose or miglitol, the efficacy of the latter is reduced, so concomitant use should be avoided.

Product Method of Bulk Pancreatin Powder.