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promethazine hydrochloride Usage and Function.

1. Skin and mucous membrane allergy: suitable for long-term, seasonal allergic rhinitis, vasomoconstrictive rhinitis, allergic conjunctivitis caused by contact with allergens or food, urticaria, angioneurotic edema, allergic reaction to blood or plasma products, skin scratches. If necessary, it can be used in combination with epinephrine as an adjunct to this medicine.

2. Motion sickness: prevention and treatment of car sickness, sea sickness and plane sickness.

3. Sedation and hypnosis: applicable to pre-operation, post-operation and obstetrics. In addition, it can also be used to reduce the fear of adults and children, showing a light sleep state.

4. Treatment of nausea and vomiting: It is suitable for some anesthesia and postoperative nausea and vomiting, and is also used to prevent and treat radiation sickness or drug-induced nausea and vomiting.

5. Postoperative pain: It can be combined with painkillers as an adjunct medication.

Uses of promethazine hydrochloride.

It can competitively block the Hl receptor in the limbs of the group and produce antihistamine effect, which can resist the capillary dilatation caused by histamine, reduce its permeability and relieve the wheezing caused by the contraction of bronchial smooth muscle. The effect is stronger and longer than diphenhydramine hydrochloride. Suitable for various allergic diseases and vomiting during pregnancy.

Pharmacological action of promethazine hydrochloride.

Promethazine is a phenothiazine antihistamine, and can also be used for nausea, motion sickness, and sedation and hypnosis.

1. Antihistamine effect: Competing with histamine released by tissues for H1 receptors, it can antagonize the contraction or contracture of the smooth muscle of the gastrointestinal tract, trachea, bronchus or bronchioles, and relieve the spasmodic and congested effect of histamine on the smooth muscle of the bronchus.

2. Antiemetic effect: It may be related to inhibiting the emetic chemical receptive area of the medulla oblongata.

3, anti-motion sickness: It may act on vestibular and vomiting centers and medulloid receptors in the midbrain through central anti-cholinergic activity, mainly blocking the excitation of cholinergic synaptic labyrinth impulse in vestibular nucleus.

4, sedative hypnotic effect: may indirectly reduce the irritability of the brain stem ascending reticular activation system.

Product Method of Bulk promethazine hydrochloride Powder.

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