Iron Fumarate Raw materials Powder Iron Fumarate

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Iron Fumarate Powder Usage and Synthesis.

Ferrous fumarate is absorbed in animals as ferrous ions in the duodenum and upper jejunum.

Most of the absorbed iron is involved in the synthesis of hemoglobin in the bone marrow, and the remainder is stored as ferritin and ferrohemoglobin in the reticuloendothelial cells of the bone marrow, liver, and spleen, with an additional portion present in the cells of the intestinal mucosa.

This absorption method is different from inorganic iron supplements (ferrous sulfate, ferrous carbonate and iron oxide, etc.), which can alleviate the competitive antagonism between trace elements when absorbed, does not destroy vitamins, and does not catalyze oxidation reactions, and each nutrient has a good compatibility, and can pass the body's absorption barrier, not only greatly improve the absorption and utilization of iron, but also improve the absorption rate of other elements.

Iron is excreted mainly through the intestinal tract and the skin, with small amounts also excreted in the urine and sweat glands. Most of the iron can be reused when it is released after the hemoglobin molecule is destroyed.

Uses of Iron Fumarate.

Ferrous fumarate, as a food iron fortifier, is better absorbed than inorganic iron. In China, it can be used in salt and sandwich candies at 1800-1600mg/kg; in high-iron cereals and their products (daily limit of 50g of such foods) at 520-580mg/kg; in dairy products and infant foods at 180-300mg/kg; in cereals and their products at 70-150mg/kg; and in beverages at 30-60mg/kg. kg.

Ferrous fumarate is an anti-anemia drug. Anemia is divided into iron deficiency anemia, megaloblastic anemia and aplastic anemia according to different etiologies. Ferrous fumarate is used for the treatment of iron deficiency anemia, which has high iron content, good absorption, and is difficult to be oxidized into trivalent iron, and the serum iron value rises soon after serving and can be kept stable. The oral LD50 of mice is 480mg/kg.

Characteristic of Iron Fumarate.

Product Method of Bulk Iron Fumarate Powder.

It is obtained by replacing sodium transbutylene diacid with ferrous sulfate. Heat water to boiling, add transbutylene succinate with stirring, add sodium carbonate to pH=6.5-6.7 in stages, stir well and filter while hot, get sodium transbutylene succinate solution.

Add ferrous sulfate solution, stirring and heating reflux 3-4h, cooling crystallization, shake filter. The filter cake is washed with distilled water until the sulfate meets the requirements, dry, get ferrous fumarate, yield 83%.

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