Related Attributes
Product details
Nicotinic Acid, the immediate precursor to NAD+, is a vital micronutrient that the body uses to turn food into energy. While often confused with Nicotinamide (which doesn't cause a flush), Nicotinic Acid is the form clinically studied for its significant impact on cholesterol levels and peripheral circulation.
Customizable Dosage: Precisely scale your intake based on individual tolerance or formulation requirements.
Zero Fillers: Unlike tablets, our pure powder contains no magnesium stearate, silicon dioxide, or artificial coatings.
Cost-Efficiency: Ideal for bulk purchasing for wholesale or long-term personal use
Niacin is a precursor of the coenzymes NAD and NADP. It is widely distributed in nature and is found in abundance in liver, fish, yeast and cereals. Dietary deficiencies have been associated with pellagra. The term "niacin" is also used for niacinamide or other derivatives with niacin bioactivity. Vitamin (enzyme cofactor).
Niacin is mainly used as feed additives, which can improve the utilisation rate of feed protein, milk production of dairy cows and meat production and quality of fish, chickens, ducks, cows, sheep and other livestock.
Nicotinic acid is also a widely used pharmaceutical intermediates, with its raw materials, can be synthesised into a variety of pharmaceuticals, such as nicosamide and nicotinic acid inositol ester.
In addition, nicotinic acid also plays an irreplaceable role in luminescent materials, dyes, electroplating industry and other fields.
If you need more information, please contact us. >>
Uses and functions of Nicotinic acid.
This product is a vitamin drug, and niacinamide collectively known as vitamin PP, used for anti-hirsutism, can also be used as blood expansion drugs, a large number of food and feed additives.
As a pharmaceutical intermediate, it is used in the production of isoniazid, nicotinamide, nicosamide and inositol nicotinate.
Niacin is an important hydrogen transporter and anti-mange factor in the organism, maintains the health of skin and nerves, and promotes the role of digestion. Dosage 30-80mg/kg.
Niacin is an important hydrogen transporter and anti-mange factor in organism tissues, maintaining skin and nerve health and promoting digestion.
China's regulations can be used to fortify cereals and their products, the use of 40-50mg/kg; in the fortification of baby food use 30-40mg/kg; in the drinking liquid and milk drinks use 10-40mg/kg.
In addition, it can be used as feed additives and colouring auxiliaries for meat products.
Niacin vs Niacinamide
| Comparison Dimensions | Niacin | Niacinamide |
|---|---|---|
| Mechanism of Action | 1. Directly activates G protein-coupled receptors to regulate lipid metabolism; 2. Converted into niacinamide, participates in nicotinamide adenine dinucleotide (NAD) synthesis (maintains cellular energy). |
1. Does not directly act on lipid receptors; must first convert to NAD; 2. Core function is as a precursor to NAD, supporting cellular repair and energy metabolism. |
| Lipid-lowering effect | Significant. High doses (1-3g/day) reduce “low-density lipoprotein (bad cholesterol)” and triglycerides while increasing “high-density lipoprotein (good cholesterol)”, serving as a clinically proven adjunct lipid-lowering agent. | None. Even at high doses, it does not affect lipid levels and is used solely for vitamin B3 supplementation. |
| Side Effects | Noticeable “flushing” (90% of users experience): facial/neck warmth, itching, tingling (caused by vasodilation, resolves in 15-30 minutes); high doses may cause liver damage or hyperglycemia. | No flushing. Exceptionally well-tolerated; no significant side effects at standard doses (100-500mg/day), with high long-term safety. |
| Absorption and Metabolism | Rapid absorption after oral intake, though efficiency decreases at high doses; requires conversion to nicotinamide in the liver for core physiological functions. | More stable absorption; directly participates in NAD synthesis without liver conversion, resulting in lower metabolic burden. |
| Natural Food Sources | Rich sources: animal liver, lean pork, tuna, peanuts, whole grains, legumes | Less abundant in natural foods; primarily generated from niacin conversion within the body; present in small amounts in dairy products and eggs |
Function of Nicotinic acid.
Constitutes nicotinamide adenine dinucleotide (Coenzyme I, NAD+ or CoI) and nicotinamide adenine dinucleotide phosphate (Coenzyme 11, NADP+ or CoII) Nicotinamide binds to adenine, ribose, and phosphoric acid in vivo to constitute nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate, which act as electron carriers or hydrogen transporters in biological redox reactions that depend on molecular structure Nicotinamide part.
The nicotinamide pyridine ring has reversible hydrogen- and electron-addition and dehydrodegeneration properties, transferring hydrogen and electrons during enzymatic reactions. Glucose Tolerance Factor (GTF) is a complex of trivalent chromium, niacin, and glutathione, and is an insulin cofactor that increases glucose utilisation and promotes the conversion of glucose to fat.
Niacin reduces blood cholesterol, triglyceride and beta-lipoprotein concentrations and dilates blood vessels.
Product Method of Bulk Nicotinic acid Powder.
It is obtained from 3-methylpyridine by oxidation and acidification. Another method using 3-methylpyridine as feedstock is gas phase oxidation with ammonia. Using a fluidised bed reactor, 3-methylpyridine, air and ammonia are mixed proportionally and reacted at 290-360 under the action of a vanadium catalyst.
The fumonisole obtained was hydrolysed with sodium hydroxide at 160°C. If the hydrolysis is carried out with ammonia, the solubility of the hydrolysis is controlled to obtain nicotinic acid or nicotinamide, respectively. Nicotinic acid can also be produced from nicotine (tobacco).
Fluidised bed reactor is used, with ferric ammonium citrate as catalyst, and gas phase oxidation with air at 65-105 °C.
Nicotinic acid can also be produced industrially from quinoline, which is commonly oxidised and decarboxylated by ozone or oxidised and decarboxylated by nitric acid.
FAQ
A: No. Despite the similar name, they are chemically distinct. Nicotinic acid is an essential vitamin (B3) and does not have the addictive properties or health risks associated with nicotine.
A: Store in a cool, dry place away from direct sunlight. Our moisture-proof, re-sealable packaging is designed to maintain a shelf life of up to 2 years.
A: Yes, many of our clients in the European skincare industry use Nicotinic Acid powder in topical applications to support skin barrier function and circulation.
A: Our Nicotinic Acid is produced in GMP-certified facilities. While we provide the raw material, we recommend that formulators ensure their final products meet specific local labeling requirements.
Our Strengths
We possess extensive experience, handling every step from sourcing each ingredient in the formulation to post-filling inspection, all at the most competitive prices and with the fastest delivery times.
InterlGroup owns factory, Main Product Foods additives, Nutritional supplements, Healthcare Products(capsules,Softgels,tablets,Gummies,Liquid Drops,Gum,solid beverage and other customized products), plant extracts.
Support OEM&ODM service，Design label packaging, Overseas in stock, Fast customization, Drop Shipping.
Intergroup is supplying OEM service for the Well-known brands Reson and Ausreson.
Alibaba International Station No.1 supplier, Alibaba International Station Number 1, Alibaba International Station Number one.
Поставщик оптовых партий порошка ниацина (никотиновой кислоты) чистотой 99%.
Fournisseur en gros de poudre de niacine (acide nicotinique) pureté 99%.
Großhandelslieferant für 99% reines Niacin (Nikotinsäure) Pulver.
Proveedor al por mayor de polvo de niacina (ácido nicotínico) con pureza del 99%.
Fornecedor de granel de pó de niacina (ácido nicotínico) com pureza de 99%.
WHY CHOOES US?
OUR CERTIFICATE
CUSTOM PROCESS
OUR PACKAGE
OUR EXHIBITION
OUR FACTORY
Shipping
Pharmaceutical Intermediate manufacturers
©2022 Xi'an Henrikang Biotech Co., Ltd.,
Home
E-mail
Booking