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L-Ornithine L-aspartate salt is an important bioactive substance with a wide range of applications. First, it plays a key role in the urea cycle and ammonia detoxification, forming arginine and splitting urea.
Secondly, L-aspartate is involved in the synthesis of nucleic acids in liver cells, which helps repair damaged liver cells. In addition, L-Aspartic Acid indirectly promotes the metabolic process of the tricarboxylic cycle in hepatocytes, which can promote energy production in hepatocytes and restore the function of damaged hepatocytes.
L-Ornithine L-Aspartate salt is also involved in the ornithine cycle, promoting the metabolism of ammonia and carbon dioxide, and reducing the levels of ammonia and carbon dioxide in the blood. At the same time, L-Aspartic Acid can also act as a carrier for potassium ions, allowing them to enter the cells.
Uses of L-ornithine L-aspartate.
L-Ornithine L-Aspartate Salt was first recognized by clinicians in correcting hepatic encephalopathy and subclinical forms of hepatic encephalopathy. With the progress of clinical research, L-Ornithine L-Aspartate Salt has been found to have a role in hepatocyte protection and repair, reducing hepatocyte damage, and decreasing hepatic inflammatory response.
At present, L-ornithine L-aspartate salt has been used as a hepatoprotective drug in the treatment of various chronic hepatitis, drug-induced liver damage, fatty liver and other diseases. The latest study on NMDA receptor further confirmed the anti-inflammatory effect of L-ornithine L-aspartate on the inflammatory factor regulatory pathway, and this new anti-inflammatory mechanism of action is also very valuable for research in future clinical studies.
Pharmacological effect of L-ornithine L-aspartate.
Mentholated ornithine provides a substrate for urea and glutamine synthesis in the body. Glutamine is a detoxification product of ammonia as well as a storage and transportation form of ammonia.
Under physiological and pathological conditions, urea synthesis and glutamine synthesis are affected by ornithine, menthionine, and other dicarboxylic compounds. Ornithine is involved in almost the entire process of activation of the urea cycle and detoxification of ammonia.
Arginine is formed in this process, followed by the separation of urea to form ornithine. Menthionine is involved in the synthesis of nucleic acids in hepatocytes to facilitate the repair of damaged hepatocytes. In addition, due to the indirect promotion of the metabolic process of the tricarboxylic acid cycle in the hepatocyte by Mentholatum, it promotes the energy synthesis in the hepatocyte, which facilitates the repair of the damaged hepatocyte and accelerates the recovery of liver function.
Product Method of L-ornithine L-aspartate.
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