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Nobiletin Usage and Function.

Chuan chenpiin (Nobiletin) is a polymethoxyflavonoid found in some citrus fruits with a variety of pharmacological effects, including anti-inflammatory, anti-tumor and neuroprotective properties.

A team of researchers led by the Heart Institute at the University of Ottawa, Canada, found through mouse experiments that chuanpiensin can counteract the adverse effects caused by a high-fat diet, thereby improving metabolic dysregulation and preventing postprandial hyperlipidemia.

Previous epidemiologic studies have shown that higher flavonoid intake is associated with lower cardiovascular risk. Therefore, Kawecheapitin should also have a role in reducing disease risk.

Nobiletin Powder

Uses of Nobiletin.

Chuan chenpianin is a flavonoid with anticoagulant, antithrombotic, anticancer, antifungal, anti-inflammatory, antiallergic, anticholinesterase and antiepileptic properties. In addition, Chuan Chenpi pigment can promote carbohydrate metabolism.

A team of Canadian researchers found that chuanpianin was effective in lowering the level of triglyceride-rich proteins after a meal, and also promoted the clearance of triglycerides to reduce their accumulation in the intestinal tract. In addition, it can increase AKT/FoxO1 phosphorylation levels to increase insulin sensitivity, thus lowering blood glucose levels.

Chuanpianin also prevents high-fat diet-induced metabolic dysregulation and reduces atherosclerosis, VLDL-triglyceride secretion, and hepatic triglyceride accumulation through multi-tissue effects.

Nobiletin