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Phytosterols have a wide range of biological functions in medicine and food science. In animal production, the scientific use of phytosterols can promote animal growth, improve the health of the body, improve the quality of livestock products, for reducing the cost of breeding, improve economic efficiency has a positive effect. As a functional additive, phytosterols have a broad application prospect in the feed industry.
At present, on the phytosterols to improve animal growth and health in the role of mechanism, effective dosage and dose, absorption efficiency and application technology has not yet been fully elucidated, but also need to do a large number of in-depth research, to lay the foundation for its scientific and rational application.
Uses of Beta-sitosterol.
It has the effects of lowering cholesterol, relieving cough, expectorant and inhibiting tumor and repairing tissues. It is used for type II hyperlipidemia, atherosclerosis and chronic bronchitis, also used for early cervical cancer and skin ulcers.
Gastrointestinal reactions such as loss of appetite, diarrhea and gastrointestinal pain can occur in large doses. Ulcers caused by osteomyelitis should not be used before the primary disease is healed. Calf ulcers accompanied by varicose veins of the lower extremities must be treated simultaneously with varicose veins.
Beta-sitosterol has cholesterol-lowering, cough-relieving, expectorant and tumor-inhibiting and tissue-repairing effects. It can be used as lipid-lowering drug for type II hyperlipidemia, atherosclerosis and chronic bronchitis, also used in early cervical cancer and skin ulcers.
Side effects of Beta-sitosterol.
Gastrointestinal reactions such as loss of appetite, diarrhea, and gastrointestinal pain may occur at high doses. Ulcers caused by osteomyelitis should not be used until the primary disease has healed. Calf ulcers accompanied by varicose veins in the lower extremities must be treated concurrently with varicose veins.
Product Method of Bulk Beta-sitosterol Powder.
To rice bran oil offal as raw material raw material processing take methyl alkali soap residue at a constant temperature of 80 ℃ below the oven drying, so that the moisture content is less than 2%, get dry soap residue, small granular or powder.
Methyl alkali soap residue [80 ℃ below] → dry soap residue extraction take dry soap residue added to the enamel reaction tank, add acetone (V soap residue: V acetone = 1: 8) stirring, jacketed distillation steam heating, reflux extraction at 50-55 ℃ 3-4h, cooled to 30 ℃ discharge at 10-15 ℃ static 12h, pressure filtration, the filtrate.
Dry soap residue [acetone] → [50-55 ° C, 3-4h] filtrate concentration, crystallization, drying the filtrate into the concentration tank, concentrated to the original volume of 1 / 5, to get the concentrate, room temperature standing crystallization 12h, filtration, to get the crude product, 60 ° C oven drying, to get the dry crude product.
Filtrate [concentration] → concentrate [crystallization] → crude products [60 ℃] → dry crude products decolorization, crystallization, drying take dry crude products plus 25-30 times 95% ethanol, add hydrochloric acid pH3-4, water bath heating, so that the crude product is dissolved, add 10-20g / L activated carbon micro-boiling for 20min, while hot, filtration, filtration, get filtrate, room temperature static crystallization for 12h, to be precipitated by the crystallization of the more complete, filtration. Collect the crystallized product, dry under vacuum at 80 ℃, get steroidal alcohol finished products.
Dry crude products [decolorization] → filtrate [crystallization] → crystalline products [below 80 ℃] → steroidal alcohol products.
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