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Invertin is an xanthone compound extracted from the plant mangosteen, which has a variety of biological activities, including inhibition of protein kinase phosphorylation, cancer cell proliferation, apoptosis, angiogenesis and metabolism.
In addition, α-inverted twistorin is also used in breast cancer treatment to inhibit cancer cell growth and promote cancer cell apoptosis. The α-inverts in mangosteen extract also have antioxidant, anti-inflammatory and antibacterial effects.
Due to the safety and non-toxicity of α-invertin and its long history of consumption, its research as a drug provides a theoretical and application basis.
Uses and functions of Mangostin.
α-Inverted Twist has been shown to be useful in the treatment of diarrhoea, malaria, anti-inflammatory, anti-ulcer, and anti-leukaemia and septicaemia.
It has antioxidant, anti-inflammatory, antibacterial and anticancer pharmacological activities.
Pharmacological Effect of Mangostin Powder.
1、Inhibition of cyclooxygenase
Cyclooxygenase is involved in a variety of pathophysiological processes, its high expression on inflammation, pain, cardiovascular disease, Alzheimer's disease, cancer, the occurrence and development of all stages of the promotion of the role of obvious. γ - invertin can be combined with the active point of the cyclooxygenase, can be completely inhibited by cyclooxygenase activity. α - invertin also inhibit the activity of the cyclooxygenase, the range of inhibitory concentrations similar to that of the γ - invertin.
2, Phytoestrogen-like effect
The biological effect of phytoestrogens is mainly manifested in hormone-related diseases, such as breast cancer, cardiovascular disease, osteoporosis, menopausal syndrome, etc. α-invertin has therapeutic effect on hormone-related diseases.
3、Apoptosis
The apoptotic effect of α-invertegrin makes it provide a new way for the immunotherapy of leukaemia.
4、Inhibition of neurosphingosine phosphatase
Neurosphingosine phospholipase is the hydrolase of nerve sheath phospholipids, which is involved in the regulation of cell growth, differentiation, apoptosis and other processes. It has a great relationship with the occurrence of intestinal tumours. α- can inhibit the activity of neurosphingosine phospholipase.
5、Antioxidant effect
The oxidation of low-density lipoprotein is very harmful to cardiovascular disease and other chronic diseases.
Synthetics of Bulk Mangostin Powder.
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