Antibiotics raw material Danofloxacin Mesylate Powder

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Danofloxacin Mesylate Powder Usage and Synthesis.

Danofloxacin is a synthetic antimicrobial agent of the fluoroquinolone class that acts primarily through inhibition of bacterial DNA-promoter enzymes, which are necessary for DNA super-helixation to provide proper spatial arrangement of DNA in the bacterial cell.The minimum inhibitory concentration (MIC) of Danofloxacin, resistant to 90 per cent (MIC90) contemporary European and North American regional Pasteurellahaemolytica, Pasteurellamultocida and Haemophilussomnus, the most important respiratory pathogens of livestock, was 0.125 µg/ml.

Uses of Danofloxacin Mesylate.

For infections of livestock and poultry (G+) bacteria, certain anaerobes, mycoplasma and helminths.

1. lung infections caused by a mixture of Staphylococcus aureus, Streptococcus haemolyticus, Pneumococcus, Legionella pneumophila;

2. avian chronic respiratory disease caused by Mycoplasma, porcine asthma;

3. swine proliferative enteritis, dense spirochete dysentery, toxoplasmosis;

4. necrotising enteritis in chickens;

5. pet actinomycosis.

Physiological Effects of Danofloxacin Mesylate.

Darifloxacin mesylate has strong antibacterial effects mainly against Gram-positive bacteria (G+), certain anaerobes and mycoplasmas. It is sensitive to Streptococcus aureus, Streptococcus haemolyticus, Pneumococcus, Legionella pneumophila, Mycoplasma, and also sensitive to Clostridium difficile, Clostridium weissei, Tetanus, Mycobacterium avium.

Dafloxacin mesylate is clinically used for infections caused by epimycin-resistant and erythromycin-resistant bacteria; mycoplasma infections caused by avian chronic respiratory disease and porcine asthma; necrotising enteritis in chickens; porcine dense spirochete dysentery, toxoplasmosis; pet actinomycosis.  

Caveat of Bulk Danofloxacin Mesylate Powder.

1、Darfloxacin mesylate is synergistic with aminoglycosides;

2, sometimes can cause diarrhoea, rash and other allergic symptoms, stop the drug will disappear.

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