Omeprazole Raw Material Omeprazole Powder

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Omeprazole Raw Materials Usage and Synthesis

China Omeprazole Raw Material Manufactory Omeprazole Powder Factory Supply Omeprazole Raw Material, High Quality Omeprazole Powder Purity 99% Omeprazole Raw Powder CAS 73590-58-6 Omeprazole Raw Powder. Omeprazole Raw Material is used for gastric and duodenal ulcers, stress ulcers and others.

Uses and functions of Omeprazole Powder

• 1. For gastric and duodenal ulcers, stress ulcers, etc.
• 2. For reflux oesophagitis, gastrinoma.
• 3. This injection can also be used for:

1. ① peptic bleeding, such as peptic ulcer bleeding, anastomotic ulcer bleeding, etc., as well as the prevention of upper gastrointestinal bleeding caused by severe diseases (such as cerebral haemorrhage, severe trauma, etc.) and after gastric surgery.
2. ② Acute gastric mucosal injury complicated by stress or caused by non-steroidal anti-inflammatory drugs.
3. ③ After general anaesthesia or major surgery and in comatose patients to prevent acid reflux and aspiration pneumonia.
4. 4. Combined with amoxicillin and clarithromycin, or with metronidazole and clarithromycin, it can effectively kill Helicobacter pylori (Hp).

Pharmacological Effects of Omeprazole Raw Powder

Omeprazole Powder is a kind of proton pump inhibitor that can effectively inhibit gastric acid secretion, and the trade names circulating in the market include antigastric piperazole, omidazole, subfontal imidazole, Losec, methoxsulphonazole, wobbizole, Womeprazole, belonging to the acid-suppressing class of drugs, and common acid-suppressing class of drugs also include pantoprazole, rabeprazole, esomeprazole, and the mechanism of action is to act on the gastric mucosal wall cells selectively.

Production method of Raw Omeprazole Powder

3,5-Dimethyl-2-hydroxymethyl-4-methoxypyridine was chlorinated to produce 2-chloromethyl-3,5-dimethyl-4-methoxypyridine.4-Methoxy 1,2-phenylenediamine was reacted with potassium xanthate to produce 2-mercapto-5-methoxybenzimidazole, which in turn was reacted with pyridine derivatives obtained above to produce 2-[(3,5-dimethyl-4-methoxy-2-pyridinyl)methylthio ]-5-methoxy-1H-benzimidazole, and finally oxidised with m-chloroperbenzoic acid in chloroform at 5°C to give omeprazole. The crude omeprazole can be recrystallised with acetonitrile.

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