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Honeysuckle extract has been widely used in pharmaceutical, fragrance, cosmetics, health food, health beverage and other fields. In the pharmaceutical aspect, it has developed from the traditional Chinese medicine formula to tablet, injection, pill, powder, paste and other types: in the fragrance industry has developed honeysuckle perfume, honeysuckle shampoo and so on; In terms of beverages, we have developed honeysuckle tea, honeysuckle shower, silver malt beer and other products, which are favored by domestic and foreign consumers.
Pharmacological action of lonicera caprifolium extract.
1. Anti-inflammatory, antipyretic, anti-allergic effect
The extract of honeysuckle can inhibit carrageenan foot swelling and reduce the degree of egg white foot swelling in rats. It also had obvious anti-exudation and anti-proliferation effect on the oily granulation sac of croton in rats. Honeysuckle flower has obvious antipyretic effect on experimental animal febrile model. Yinqiao Powder can significantly inhibit a variety of experimental inflammation, especially allergic inflammation, and can significantly inhibit 2, 4-dinitrophenol induced fever in rats.
2. Anti-fertility effect
The decoction after ethanol extraction of honeysuckle has obvious anti-fertility effect without oral administration, and it is effective for early, middle and late pregnancy in mice when injected intraperitoneally, and it is also effective for early pregnancy in rabbits when given intravenously or intrauterine. The plasma progesterone of early pregnancy rats can be significantly decreased by honeysuckle, and the anti-early pregnancy effect of honeysuckle can be completely cancelled by exogenous progesterone and chorionic gonadotropin (HCG). Honeysuckle can also significantly inhibit the formation of deciduoma in pseudopregnant mice, and this effect can also be resisted by progesterone.
3. Antioxidant effect
The aqueous extract of honeydew has a direct elimination effect on hydrogen peroxide (H2O2) in vitro with a linear dose-effect relationship, but whether it also has an effect in vivo remains to be further studied. In addition, honeysuckle flower can improve the release of H2O2 from neutrophils of scalded mice to a certain extent, and can reduce the ability of neutrophils to synthesize and release lysosomal enzyme, indicating that it has the effect of antioxidant reaction. The results showed that both chlorogenic acid extract and crude flavone had significant inhibition on the peroxidation of oil. Lonicerin and chlorogenic acid are two phenolic acid compounds with high content in honeysuckle leaves. Phenolic acid is a kind of typical compound with free radical scavenging effect, while lonicerin is slightly stronger than chlorogenic acid. DPPH method was used to study the antioxidant activity of Flos lonicerae, and the inhibitory rate was used to express the antioxidant activity. When the mountain silver flowers thick.
Uses of lonicera caprifolium extract.
Product method of Bulk lonicera caprifolium extract Powder.
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