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Fluoxetine hydrochloride can be used for all types of depression, especially for organic diseases accompanied by depressive symptoms and senile depression. It is also used to treat post-schizophrenic depression. It is also used for obsessive-compulsive disorder, phobia, anxiety symptoms of depression, bulimia nervosa, weight loss and as an adjunct to smoking cessation.
Uses and functions of Fluoxetine hydrochloride.
Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI) for the treatment of a variety of depressive mental disorders, including minor or major depression, bipolar affective disorder depression, psychogenic depression, and depressive neurosis. The mechanism of action is to inhibit the uptake of serotonin by neurons from the synaptic gap, increasing the availability of this neurotransmitter in the gap, thereby improving emotional states and treating depressive mental disorders. Common adverse reactions were dry mouth, loss of appetite, nausea, insomnia, fatigue, and anxiety and headache in a few cases. Due to the long half-life of fluoxetine hydrochloride, the dose should be appropriately reduced in patients with poor liver and kidney function or elderly patients. Children should follow the doctor's advice when using. Use with caution in people with a history of epilepsy, pregnant or lactating women. If rash or fever occurs, stop taking the medicine immediately and treat the symptoms. It should not be combined with monoamine oxidase inhibitors (MAOI). If necessary, this drug should be discontinued for 5 weeks before switching to monoamine oxidase inhibitors (MAOI).
Pharmacological action of Fluoxetine hydrochloride.
Fluoxetine blocks the 5-HT2A receptor and restores DA and NE levels by inhibiting the 5-HT2A receptor. At the same time, fluoxetine can also relieve the inhibition of NE and DA release by GABA neurons through 5-HT2C receptor. In addition to increasing the concentration of 5-HT in the synaptic cleft, it is based on fluoxetine's effect on 5-HT2A and 5-HT2C that the levels of DA and NE are directly and indirectly restored, with NE and DA deinhibition properties (NDDI).
Product method of Bulk Fluoxetine hydrochloride Powder.
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