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Nathamycin is a ‘polyene macrolide’ fungal inhibitor produced by the fermentation of Streptomyces natalis, and is currently the only internationally approved antifungal biofood preservative with high efficiency, broad-spectrum, safety and natural properties.
Natamycin relies on its lactone ring structure to interact with sterols on fungal cell membranes to form sterol compounds, thereby destroying the structure of the cytoplasmic membrane. The hydrophilic portion of the macrolide forms water pores in the membrane, impairing cell membrane permeability, which in turn causes the exudation of amino acids, electrolytes, and other substances from the fungus, and the death of the fungus.
Because, as a polyene antibiotic natamycin mechanism of action is to bind the sterols on the fungal cell membrane. The cell surface of animal organism lacks sterol, and it is not sensitive to polyene antibiotics.
Therefore, natamycin is harmless to human body, and it is difficult to be absorbed by human digestive tract. No mutagenic, carcinogenic and sensitising effects. It is a natural antifungal agent, possessing the characteristics of safety, high efficiency, natural and health.
Uses and functions of Natamycin.
An antifungal polyene antibiotic that inhibits fungal growth by specifically binding to ergosterol. Unlike mycobacteria and phlebotinum, natamycin does not alter the permeability of cell membranes.
Anti-mould agents. Good anti-mould effect when used on air-exposed food surfaces where moulds tend to proliferate. Used in fermented cheese, it can selectively inhibit the propagation of moulds and allow the normal growth and metabolism of bacteria.
Preparation method of Natamycin.
Product method of Bulk Natamycin Powder.
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