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The induction of paclitaxel biosynthetic pathway was induced at 0, 0.1, 1, 10, and 20 μmol/L ammonium citrate to observe the changes in the yield of paclitaxel analogues and to qualitatively analyze them by biometabolic pathways.
The results showed that the yield of paclitaxel was increased nearly 3-fold under the induction of 10 μmol/L ammonium citrate, while the concentration of 10-DAB and baccatin III showed a decrease, which showed a degree of negative correlation with the concentration of paclitaxel. By kinetic analysis, it was pointed out that ammonium citrate addition increased the reaction rate of the reaction from baccatin III to paclitaxel interactions.
Uses of Triammonium Citrate.
Ammonium citrate (AmmoniumCitrate) also known as ammonium citrate, triammonium citrate, ammonium citrate, white crystalline powder, ammonia odor, soluble in water and acid, aqueous solution is acidic, insoluble in ethanol, ether and acetone. Easily deliquescent, decomposed when heated to melting point, non-toxic.
Citric acid monohydrate as raw material, refined and extracted. Mainly used in chemical analysis (such as the determination of phosphate in fertilizer), industrial water treatment, metal cleaning, cyanide-free plating complexing agent, ceramic dispersant, detergent raw materials, and soil conditioner components.
Chemical properties of Bulk Triammonium Citrate powder.
Product Methods of Triammonium Citrate.
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