Natural Hydrocotyle Asiatica Extract Powder

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Hydrocotyle Asiatica Extract Powder Usage and Synthesis.

Centella Asiatica Extract is an ingredient extracted from Centella asiatica that has a variety of effects. It reduces the production of pro-inflammatory mediators and improves and repairs the skin's own barrier function, thus preventing and correcting skin immune dysfunction.

In addition, Centella asiatica extract has significant anti-inflammatory effects and can be used to treat diseases such as damp-heat jaundice, heat stroke and diarrhoea, sand and blood drenching, carbuncle, swelling and sores, and bruises and injuries. Centella asiatica extract contains a variety of triterpenoids, including the structure of α-vanillinol, the main components of which are centella asiatica glucoside and hydroxycentella asiatica glucoside.

In addition to its medicinal uses, Centella asiatica extract is also widely used in cosmetics and wet wipes for its repairing and soothing properties.

Uses of Hydrocotyle Asiatica Extract.

Centella asiatica extract can be used to treat gastric ulcer, hypertension, skin diseases such as intractable wounds, skin tuberculosis, leprosy and so on.

It is mainly used clinically for the treatment of chronic bronchitis, flukes carriers, hepatitis B, mumps, acute jaundice hepatitis, digestive moulds, all kinds of fever, poisoning, and nephritis, uremia and other conditions.

Individual countries and regions will be used for brain, diuretic, leprosy, skin diseases, but also as an adjuvant treatment of obesity

Pharmacological Effect of Hydrocotyle Asiatica Extract.

1.Anti-gastric ulcer effect

Centella asiatica extract can increase the level of γ-aminobutyric acid (GABA) in the brain of rats with gastric ulcer model, and also reduce the secretion of gastric acid and the activity of pepsin, which shows good anti-ulcer effect.

2.Enhancement of memory

The aqueous extract of Centella asiatica can significantly improve the memory of rats in passive avoidance response test.

3. Effects on central nervous system

Centella asiatica extract has strong central inhibitory effect and choline-like effect.

4. Antibacterial effect

The aqueous extract of Centella asiatica has antibacterial and antiviral effects, and has inhibitory effects on Pseudomonas aeruginosa, Proteus mirabilis and Staphylococcus aureus. In addition, Centella asiatica glycosides can dissolve the wax membrane of bacteria.

5.Stimulate biosynthesis

The total triterpene extract of Centella asiatica can significantly affect the cell proliferation and protein and proteoglycan biosynthesis, so that collagen and fibre-binding protein increased significantly.

6.Actions on skin tissues

It can accelerate wound healing, promote skin growth, local leukocytosis, connective tissue vascular network proliferation, increased mucus secretion.

7.Other effects

The crude extract of Centella asiatica given orally to female rats showed significant and long-lasting activity in reducing fertility; lowering cardiac systolic blood pressure and heart rate; antiviral, anti-stress, anti-stress effects.

Extraction Method of Bulk Hydrocotyle Asiatica Extract Powder.

1.Extraction and separation test of total glycosides of Centella asiatica

Centella asiatica (whole grass) 75% ethanol extraction, the extract over liquid and concentrated under pressure to no alcohol taste, with a little petroleum ether extraction to remove chlorophyll, the concentrated solution through the macroporous resin, first a small amount of water to wash, and then eluted with 50% of the ethanol, the eluate is concentrated, vacuum drying, dried with a little distilled water to dissolve, with concentrated hydrochloric acid to adjust the pH for 3 to 4, precipitation of some of the weakly acidic substances, add chloroform extraction, to remove the lipid Soluble impurities, add concentrated ammonia to adjust pH 6 to 7, and then extracted with water saturated n-butanol for three times, the extract is recovered under reduced pressure to nearly dry, and then add 95% alcohol to dissolve a little, low-temperature vacuum drying that is, to obtain the refined products. With the remaining amount of iodine method to determine the content of more than 93%.

2.Centella asiatica extract (9%) production process

Herbs crushed into coarse powder, reflux extraction with 70% alcohol, extract, extract decompression recovery of ethanol to exhaustion, centrifugation of concentrated liquid, centrifugal liquid concentrated to 12 ~ 15 boe (thermal measurement), spray drying that is the Centella asiatica extract finished product. This process produces Centella asiatica extract containing total triterpene compounds in 9% to 10%, yield of about 20%.

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