Raw Materials Ursolic Powder

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Ursolic Powder Usage and Synthesis.

Ursolic acid, also known as ursolic acid, ursolic acid, is a pentacyclic triterpenoid extracted from the rhododendron family of evergreen trailing shrubs bearberry, with a special odour, in anhydrous ethanol to get a large and shiny prismatic crystals, and in dilute ethanol to get a fine as hair-like needle crystals.

mp285 ° C ~ 288 ° C, [α] D20 + 66 ° (pyridine), soluble in dioxane, pyridine, soluble in methanol, ethanol, butanol, butanone, slightly soluble in acetone, slightly soluble in benzene, chloroform, ether, insoluble in water and petroleum ether.

It has sedative, anti-inflammatory, antibacterial, antidiabetic, anti-ulcer, lowering blood sugar and other biological effects.

In recent years, it has been found to have anticarcinogenic, anticarcinogenic, inducing F9 teratoma cell differentiation and anti-angiogenic effects, and it is very likely to become a new type of low-toxicity and high-efficiency anticancer drugs.

In addition, ursolic acid has obvious antioxidant function, is a strong antioxidant, ursolic acid antioxidant effect on the human body's anti-aging, skin blemishes, pigmentation have a positive effect, and thus is widely used as medicine and natural whitening cosmetic raw materials, experiments have shown that ursolic acid can inhibit the metabolism of arachidonic acid in the process of 5-lipoxygenase, cyclo-oxygenase activity to prevent the generation of prostaglandins and leukotrienes, which This may be the reason why ursolic acid inhibits inflammation and lipid peroxidation.

Uses and Function of Ursolic.

Ursolic acid is a triterpenoid compound present in natural plants, which has a variety of biological effects such as sedative, anti-inflammatory, anti-bacterial, anti-diabetic, anti-ulcer, blood glucose lowering, etc. Ursolic acid also has a significant antioxidant function, in addition to demonstrating its anticancer activity through the induction of apoptosis, inhibition of cell cycle progression, inhibition of cell proliferation, inhibition of metastasis, as well as the reduction of tumourigenesis through a variety of signalling pathways.

Anti-tumour effects of Ursolic.

Ursolic acid also has resistance to a variety of carcinogenic and cancer-promoting substances, and it was found that ursolic acid can significantly inhibit the proliferation of HL-60 cells and induce their apoptosis;

It can make the macrophage phagocytosis function of mice significantly improve, and can inhibit the proliferation of human tongue squamous carcinoma cell line TSCCa cells, the inhibitor amount of half growth of TSCCa cells is about 12.5Umol-L-1, and it shows a certain quantitative effect relationship in 24h; in situ hybridisation shows that ursolic acid on TSCCa cell The inhibitory effect of ursolic acid on TSCCa cells was related to the inhibition of the in situ expression of nuclear transcription factors.

The in vivo test proved that ursolic acid can significantly enhance the immune function of the body.

This indicates that ursolic acid has a wide range of antitumour effects, and ursolic acid is very likely to become a new type of low-toxicity and effective anticancer drug.

Product method of  Bulk Ursolic Powder.

It is found in the whole grass of Prunella vulgaris L., family Labiatae, the leaves of Ilex rotunda Thunb. Ilex rotunda Thunb. is found in many plants, including the leaves of Ilex rotunda Thunb.

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