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Hydrocortisone acetate is mainly used for the treatment of rheumatoid arthritis, rheumatic fever, gout, and bronchial asthma. The injection is used for tuberculous or purulent meningitis, tuberculous pleurisy, pyothorax, arthritis, tenosynovitis, tendon strain, sprain, nodular itchy rash, lichen planus, etc. Eye drops are used for all kinds of ophthalmia. Cream is used for allergic or seborrheic dermatitis, pruritus, etc.
Uses and functions of Hydrocortisone Acetate.
For allergic, non-infectious skin diseases and some proliferative skin disorders. Such as dermatitis, eczema, neurodermatitis, seborrheic dermatitis and pruritus.
Glucocorticoid drugs with anti-inflammatory, anti-allergic, antitoxin, anti-shock effect.
Pharmacological Effect of Hydrocortisone Acetate.
Hydrocortisone acetate is an adrenocorticotropic hormone drug, also known as cortisol acetate, white crystalline powder, odourless, bitter taste. Melting point 216~222℃, right-rotating optical. Slightly soluble in ethanol, ether, chloroform, acetone, insoluble in water.
Synthesised with 17α-hydroxyprogesterone as raw material. Hydrocortisone acetate has important physiological activities, such as anti-inflammatory, antiviral, anti-allergic, anti-shock, reduce inflammatory exudation, etc., commonly used in adrenocortical insufficiency and autoimmune diseases.
There are injections, tablets, ointments and eye drops. Adding a small amount of hydrocortisone acetate in some cosmetics can increase the anti-allergic efficacy and improve the degree of skin rejuvenation, but the long-term use of such substances can lead to hormone dependence of the skin.
China's cosmetic norms stipulate that hormonal substances should not be added to cosmetics.
Product Method of Bulk Hydrocortisone Acetate Powder.
Hydrocortisone and acetic anhydride esterified in pyridine
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