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1, mycoplasma disease: Tylosin tartrate for dogs mainly used for prevention and treatment of swine mycoplasma pneumonia (swine asthma), mycoplasma gallinae infection (also known as chronic respiratory disease of chicken), infectious pleuropneumonia (also known as mycoplasma pneumonia of sheep), mycoplasma agalactia and arthritis, bovine mycoplasma mastitis and arthritis, etc.
2, bacterial diseases: a variety of gram-positive bacteria caused by the disease has a good effect on some gram-negative bacteria caused by the disease also has a good effect. Mainly used for prevention and treatment: Staphylococcus aureus caused by various suppurative diseases, streptococcus caused by bovine and sheep mastitis, swine septicemia, arthritis, piglet meningitis, equine adenopathy, traumatic infection and cervicitis, swine erysipelas caused by swine erysipelas, Pasteurella caused by swine lung disease, bovine hemorrhagic septicemia, avian cholera and sheep, horse, rabbit pasteurellosis. Salmonellosis of various livestock and poultry caused by salmonella, colibacillosis of various livestock and poultry caused by pathogenic Escherichia coli, chronic atrophic rhinitis of pig caused by Bordetella bronchoseptica, etc.
3, spirochete diseases: pig treponema caused by swine dysentery, goose borrelia caused bird spirochete disease.
4, anti-coccidiosis: can prevent and control coccidiosis.
Uses and functions of Tylosin tartrate.
Tylosin tartrate is a macrolide antibacterial drug, which has a strong effect on mycoplasma and is effective against gram-positive bacteria and some negative bacteria. Sensitive bacteria are Staphylococcus aureus, Streptococcus pyogenes, streptococcus pneumoniae, corynebacterium pyogenes and so on. Antibiotics. It is mainly used for bacterial and mycoplasma infection of livestock and poultry.
| Feature | Tylosin Tartrate | Competitors (e.g., Erythromycin) |
|---|---|---|
| Solubility | Highly water-soluble (ideal for feed/water mixing). | Less soluble; may require emulsifiers. |
| Spectrum of Activity | Effective against mycoplasma, gram-positive, and some gram-negative bacteria. | Narrower gram-negative coverage. |
| Ease of Administration | Oral (feed/water) or injectable; suitable for all livestock species. | Injectable use more common; limited oral options. |
| Regulatory Compliance | FDA/EMA-approved for veterinary use in food animals. | Varies by region; may have stricter residue limits. |
Pharmacological action of Tylosin tartrate.
Tylomycin tartrate is effective against gram-positive bacteria and some negative bacteria, but its effect is weak, and its effect on mycoplasma is stronger, and it is one of the drugs with strong effect on mycoplasma in macrolides. Tylomycin sensitive bacteria and mycoplasma are easy to develop resistance, and can produce cross-resistance with erythromycin and other antibiotics of this class. Tartrate absorption is better than phosphate absorption when tylobacterin is taken orally. Tartrate is easily absorbed from the gastrointestinal tract (mainly the intestine) after internal administration. The peak blood concentration of tylomycin was reached 1h after internal administration, and the blood concentration of tylomycin was 2 ~ 3 times higher when intramuscular injection or subcutaneous injection. Pigs excrete faster than poultry. Clinically, it is mainly used to prevent mycoplasma infection in chickens, turkeys and other animals, and has only preventive effect on mycoplasma in pigs but no therapeutic effect. In addition, tylosin is also used for staphylococcus aureus, streptococcus pyogenes, vibrio escherichia coli and spirochetes and other infections caused by pneumonia, mastitis, metritis and enteritis, but no obvious effect on Escherichia coli, Pasteurella and other infections. Tylosin can also be used to prevent coccidia infection in birds and to soak eggs to prevent the spread of mycoplasma Turkey.
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