Related Attributes
Product details
GLP-1 can also suppress appetite and ingestion, and can delay the emptying of gastric contents.
GLP-1 can be rapidly degraded in vivo by the enzyme dipeptidyl peptidase-4, referred to as DPP-4, and lose its biological activity, with a half-life of less than two minutes, greatly limiting the clinical application of GLP-1.
But the production of GLP-1 receptor agonists, can not be affected by the enzyme, directly stimulate the GLP receptor, play a good hypoglycemic effect.
GLP-1 receptor agonists not only bring excellent hypoglycemic effect, but also have good weight loss, cardiovascular and renal protection.
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Pharmacological effect of GLP-1.
GLP-1 acts on the β-cells of the pancreatic islets in a glucose-dependent manner, stimulating an increase in insulin synthesis and secretion, and can stimulate the proliferation and differentiation of the β-cells of the pancreatic islets, inhibit apoptosis, and increase the number of B-cells of the pancreatic islets. It can also strongly inhibit the secretion of glucagon from the A cells of the pancreatic islets, and can promote the secretion of growth inhibitor from the D cells of the pancreatic islets, which in turn acts as a paracrine hormone and participates in the inhibition of glucagon secretion.
Real Case Sharing.
Clinical application: Japanese medical institutions use GLP-1 for drip injection to assist in weight loss, cases show that 165cm/60kg women through the lowest daily dose of GLP-1 combined with dietary control (low-calorie balanced diet) and exercise (Pilates 4 times a week), weight loss of 5kg in 2 months, and subsequent gradual reduction of dosage to 2-3 days, resulting in an easy-to-lean physique.
Program Features:
Diet requires strict matching (e.g. milk and eggs for breakfast, mixed grain rice for lunch, vegetable soup for dinner)
Emphasizes balanced nutrition and hydration
Long-term persistent exercise is required to enhance the effect
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