Pantothenic Acid Raw materials Powder CAS:7631-95-0

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Pantothenic Acid Powder Usage and Synthesis.

D-Pantothenic acid is an important drug, food additive and feed additive with a promising market. The global consumption of calcium D-pantothenate is about 17,000 tons/year, of which the United States, Europe, Asia and Latin America are the major consumer markets.

The market for Calcium D-Pantothenate is growing steadily, and at the same time, it is also regarded as an adjuvant therapy for depression and rheumatoid arthritis, which has a broad market prospect. Pantothenic acid has the function of making antibodies in living organisms and maintains the health of hair, skin and blood. 

Pantothenic acid is also used in cosmetics because D-pantothenol can be converted into pantothenic acid, which in turn synthesizes coenzyme A, which promotes the metabolism of proteins, fats, and sugars, protects the surface of the skin and the luster of the hair, and prevents the occurrence of diseases. Pantothenic acid was first isolated and extracted from liver by scientists and later synthesized in 1940. 

Pantothenic acid is α,γ-dihydroxy-β,β'-,dimethylbutyryl-constitutional β-alanine, and upon hydrolysis, the peptide bond is severed to hydroxy acid and β-alanine.

Uses of Pantothenic Acid.

It is used in feed additives, pharmaceuticals and food additives. Sodium pantothenate is also used in beverage additives, but because of its strong hygroscopicity, it is now used instead of pantothenic acid.

D-Pantothenic acid is converted to coenzyme A (CoA) or acyl carrier protein (ACP) in vivo to participate in fatty acid metabolic reactions.CoA is a cofactor for more than 70 enzymes in living organisms (about 4% of the total amount of enzymes), and is also required by bacteria to construct cell walls.

In metabolism CoA mainly functions as an acyl carrier and participates in sugar, fat, protein and energy metabolism, and can also affect the localization, stability and activity of proteins by modifying them.

CoA provides 90% of the energy for organisms. Pantothenic acid is essential for the synthesis of steroids from fatty acids; it can also be involved in the synthesis of steroidal violet, melatonin and ferrous hemoglobin; it is also an intermediate necessary for the metabolism of the body's citric acid cycle, choline acetylation, and the synthesis of antibodies.

Therefore, D-Pantothenic acid can act on normal epithelial organs such as nerves, adrenal glands, digestive tract and skin, and improve the resistance of animals to pathogens.

Characteristic of Pantothenic Acid.

Product Method of Bulk Pantothenic Acid Powder.

Since pantothenic acid is highly hygroscopic and difficult to crystallize, it is usually made into calcium and sodium salts.D-pantothenic acid is also naturally occurring and physiologically active, and is formed by the aldol condensation of isobutyraldehyde and formaldehyde in the presence of potassium carbonate, followed by cyanation and lactonization to dl-pantothenolactone, which is then reacted with calcium aminopropionate.

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