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Piperine is a broad-spectrum anticonvulsant, with good antagonistic effects on experimental electroconvulsions in mice, and with varying degrees of antagonistic effects on convulsive seizures and audiogenic seizures induced by pentylenetetrazol, indohexadine toxin, strychnine, and intracerebroventricular injections of cylinder arrow toxins, glutamate, and so on.
Clinical trials have also shown efficacy in certain types of epilepsy. There is a folk recipe for epilepsy "white pepper and radish", and a simplified structure of piperine analogue 3-(3,4-dimethyl-dioxyphenyl)acryloylpiperidine (trade name anti-epileptic) was artificially synthesised. Piperine is more toxic to flies than pyrethrum.Extrait Standardisé de Poivre Noir : Poudre de Pipérine titrée à 98%
Characteristic of Piperine.Standardisierter Pfefferextrakt: Piperin-Pulver mit 98% Reinheit
An alkaloid with the molecular formula C17H19NO3.Стандартизированный экстракт черного перца: порошок пиперина 98% чистоты
It exists in a variety of pepper plant fruits, for its pungent flavour component, but the pungent taste of pepper mainly from its isomer Jiamicine. In the commercial black pepper and white pepper, piperine content of 5% to 9%, sometimes up to 11%.Extrato Padronizado de Pimenta-Preta: Pó de Piperina com 98% de Pureza
Piperine is colourless monoclinic prismatic crystals; melting point 130-133 ℃; soluble in acetic acid, benzene, ethanol and chloroform, slightly soluble in ether, almost insoluble in water and petroleum ether; the entrance is initially tasteless, after a pungent taste; can be generated with a strong acid crystalline salt.
The Core Scientific Mechanism of Piperine Powder in Enhancing Metabolism
1. Inhibiting ‘Piperine-4-Hydroxylase’ to Prolong the Half-Life of Metabolically Active Substances
2. Activates ‘thermogenesis’ to directly expend calories
3.Regulate adipocyte function, reducing fat storage
4. Enhancing insulin sensitivity to indirectly stabilise metabolism
Pharmacological Effect of Piperine.
Pepper is the most essential ingredient in Indian medicine and is used for the treatment of a wide range of ailments.
Pharmacological studies have demonstrated many of their traditional medicinal properties such as analgesic and antipyretic effects, antioxidant action, antimicrobial action etc. Piperine is the active ingredient of pepper.
Piperine has a wide range of pharmacological effects and has been found to have antioxidant, immunomodulatory and antitumour effects.
FAQ.
Q: Is piperine safe? Are there any side effects?
A: At recommended doses (typically 5-20 milligrams daily), piperine is safe for the vast majority of people. However, as it may affect drug-metabolising enzymes, individuals taking prescription medications (such as antihypertensives, anticoagulants, or antiepileptics) must consult their doctor before using piperine-containing supplements. This must be clearly stated by the manufacturer on the product label.
Q: What distinguishes piperine from BioPerine®?
A: BioPerine® is a proprietary piperine extract supported by relevant clinical research. Our Piperine Powder is a generic, high-purity piperine offering the same core active ingredient as BioPerine® but at a more cost-effective price point, providing brands with an alternative high-quality option.
Q: When should piperine be added to formulations?
A: Piperine should be taken alongside the core active ingredient whose absorption you wish to enhance. Therefore, during formulation, ensure both are present in the same dosage form (e.g., within the same capsule or powder serving).
Q: What are the minimum order quantities (MOQ) and sample policies?
A: Our standard MOQ is 1 kilogram. We offer paid samples of 100 grams for promising collaborative projects to support your formulation development and testing.
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Henrikang possesses the capability to manufacture any capsule formulation. From sourcing every ingredient in the formula to post-filling inspection, we undertake the entire process at the most competitive pricing and with the swiftest delivery times.
With extensive experience, we can assist you in developing new products for your target audience or discuss how to scale up production efficiently. As your partner, we are committed to achieving long-term success in capsule manufacturing.
As a leading Chinese OEM manufacturer for nutritional supplement ingredients and branded products, we hold certifications including ISO 22000, ISO 9001, HACCP, GMP, Halal, CE, CE-ROHS, Kosher, SGS, Intertek, Eurofins, and GMP. Our facility has successfully undergone US FDA inspection and registration.
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