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Copper is a component of many important enzymes in the body, can promote the absorption and use of iron, can maintain the function of the central nervous system. Copper deficiency in the body of various blood vessels and bone brittleness increase, brain tissue atrophy, can also cause vitiligo and less white head and other melanin loss disease.
Uses and functions of Copper Gluconate.
Preparation of Copper Gluconate.
Fermentation method
Taking glucose as raw material, the black mould fermentation oxidation generates gluconic acid, and then reacts with copper carbonate (or alkaline copper carbonate) to generate copper gluconate, the production equipment of this method is huge, the concentration of energy consumption is high, and it is difficult to purify and crystallise.
Direct method
Copper gluconate is generated by direct reaction between calcium gluconate and copper sulphate. This method is simple, but the residual calcium sulfate is difficult to remove.
Chemical oxidation method
Take glucose as raw material, oxidise it to gluconic acid by ozone, concentrate and dehydrate it to get gluconolactone, and then react with copper carbonate to generate copper gluconate.
Acidification method
Add 1.2mol of calcium gluconate into equal moles of sulfuric acid solution, react at 60～90℃ for 1～2h, filter out the precipitated calcium sulfate precipitate while hot, and get colourless or light yellow gluconic acid solution (relative density 1.12～1.16). 4g of aqueous barium hydroxide and 1.5g of aqueous oxalic acid were added dropwise to the above gluconic acid solution, and the reaction was stirred for 15min, to remove the residual Ca2+ and S02-. The purified solution was then passed through anion and cation exchange resin to obtain a colourless and transparent gluconic acid solution.
Another 1 mol of crystalline copper sulfate solution was mixed with 2 mol of sodium hydroxide solution and reacted at 40-60°C for 0.5-1h, filtered, and the filter cake was washed with water to obtain black copper oxide crystals. Copper oxide crystals will be added to the gluconic acid solution in batches, reaction lh, filtration to remove unreacted material, cooling and standing 3 ~ 5h after precipitation of crystals. Add appropriate amount of 95% ethanol, stirred into a paste and filtered, the filter cake at 50 ℃ vacuum drying, finished products, yield 90% ~ 92.5%.
Product Method of Bulk Copper Gluconate Powder.
Crystallised from the reaction of gluconic acid with copper oxide.
Crystallised from the reaction between gluconate and copper salt.
It is crystallised by the reaction between sodium gluconate and copper sulphate.
Obtained by electrolytic oxidation of glucose to gluconic acid and neutralisation with copper carbonate, while sorbitol is generated.
Frequently Asked Questions.
1. What is the recommended daily dose for copper gluconate powder?
The Recommended Dietary Allowance (RDA) for adults is typically around 900 micrograms per day. Due to the high concentration of copper gluconate powder, using an accurate milligram-level scale is crucial to avoid exceeding safe upper limits.
2. Should I take copper and zinc together?
Yes, but with caution. Excessive zinc intake can deplete copper levels. Many practitioners recommend a zinc-to-copper ratio of 15:1. If you consume a high-zinc diet, supplemental copper is often needed to maintain balance.
3. How should I store the powder?
To preserve potency, store copper gluconate powder in a cool, dry place away from direct sunlight. An opaque, airtight glass container is recommended to prevent oxidation.
4. Can I mix this powder into pre-workout drinks or shakes?
Yes. It dissolves highly in water. However, avoid mixing with highly acidic beverages or high-dose vitamin C, as this may disrupt the mineral structure.
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