Feed additive Raw Materials Enrofloxacin Powder

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Enrofloxacin Usage and Synthesis.

Enrofloxacin is easily absorbed by internal administration, intramuscular and subcutaneous injection, widely distributed in the body, except for the central nervous system, the drug concentration in other tissues is almost always higher than the blood concentration.

In vivo can be deethylated, mainly produce active metabolite ciprofloxacin, but the metabolism of interspecies differences in the animal body, the metabolism rate in the body of poultry, dogs, rabbits, cattle is high, and the metabolism rate in the horse, swine body is lower.

Clinical Enrofloxacin is mainly used for the treatment of respiratory, digestive, genitourinary infections, skin infections and septicaemia caused by a variety of mycobacteriosis, Escherichia coli, Salmonella, Haemophilus, Dengue bacillus, Staphylococcus, Streptococcus and so on.

It is especially suitable for mixed infections caused by a variety of bacteria.

Uses and functions of Enrofloxacin.

Enrofloxacin is a new type of veterinary antimicrobial drug with broad-spectrum and very high antimicrobial effect, which is effective against gram-positive and negative bacteria and mycoplasma. It is suitable for piglets with white diarrhoea, yellow diarrhoea, oedematous Escherichia coli, paratyphoid fever in piglets, porcine pneumonic disease, dengue, mycoplasma pneumonia, atrophic rhinitis, endemic pneumonia, pleuropneumonia, enteritis, diarrhoea, uterine inflammation, streptococcus and so on.

Pharmacological Effects of Enrofloxacin.

Enrofloxacin can be used as an animal drug, with a long half-life in animals and good tissue distribution, it is a broad-acting bacteriostatic agent with inhibitory effects on Gram-positive and negative bacteria and mould plasma, and has been used in the control of Vibrio vulnificus and Escherichia coli diseases in farmed fish.

Enrofloxacin is a synthetic third-generation quinolone antibacterial drug, also known as ethyl ciprofloxacin, which was approved by FDA on 4 October 1996, and it is a quinolone antibacterial drug for livestock, poultry and aquaculture.

It can bind to the subunit A of bacterial DNA gyrase, thus inhibiting the cleavage and linkage function of the enzyme, preventing the replication of bacterial DNA and showing antibacterial effect.

With broad-spectrum antibacterial activity and strong permeability, this product has strong killing effect on Gram-negative bacteria and good antibacterial effect on Gram-positive bacteria, well absorbed orally, with high and stable blood concentration, it can be widely distributed in tissues, and its metabolite is ciprofloxacin, which still has strong antibacterial effect.

It has strong antibacterial activity against almost all pathogenic bacteria in aquatic animals. It is effective in serious infections caused by drug-resistant pathogens and has no cross-resistance with other antimicrobials.

Characterisation of  Bulk Enrofloxacin Powder.

Enrofloxacin, also known as enrofloxacin carboxylic acid, belongs to the Fluoroquinolones (Fluoroquinolones) of the chemical synthesis of bacteriostatic agents, yellowish or yellowish crystalline powder, bitter taste, insoluble in water, soluble in sodium hydroxide solution, methanol and cyanomethane and other organic solvents.

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