Food additive Bulk Raw Acetylspiramycin Powder

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Acetylspiramycin Powder Usage and Synthesis.

Acetylspiramycin is an acetylated derivative of spiramycin, belonging to 16-membered ring macrolides. It has good antibacterial effect on Gram-positive cocci such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes and Enterococcus faecalis.

It also has inhibitory effect on Listeria monocytogenes, Catamorium monocytogenes, Neisseria gonorrhoeae, Campylobacter fetus, Haemophilus influenzae, Legionella pneumophila, Pertussis bacillus, Anaplasma phagocytophilum, Pneumocystis aeruginosa, Propionibacterium acnes, Digestive cocci and Digestive streptococci, as well as Chlamydia spp., Mycoplasma spp., Toxoplasma gondii, and Cryptosporidium. Enteric gram-negative bacilli are usually resistant to drugs.

Uses and functions of Acetylspiramycin.

Acetylspiramycin is a macrolide semi-synthetic oral antibiotic mainly used for the treatment of respiratory infections caused by bacteria such as Staphylococcus aureus, Streptococcus haemolyticus, Streptococcus grasshopperus, Streptococcus pneumoniae and Staphylococcus epidermidis, septicemia, erysipelas, scarlet fever, pharyngitis, tonsillitis, otitis media and other diseases.

For respiratory infections, pyoderma, scarlet fever, etc.

Its antibacterial spectrum, antibacterial mechanism and indications are similar to erythromycin.

Precautionary of Acetylspiramycin.

1、Because the hepatobiliary system is the main pathway for the excretion of acetylspiramycin, it should be used with caution in patients with severe hepatic insufficiency.

2, mild renal insufficiency patients do not need to make dose adjustments, but the use of acetylspiramycin in patients with severe renal insufficiency is still lack of information, so it should be used with caution.

3、If there is an allergic reaction, stop the drug immediately.

4、Pregnant women and lactating women: this product can penetrate into the placenta, so the application of pregnant women need to fully weigh the pros and cons and decide whether to apply. There is no data to show whether Acetylspiramycin is excreted through breast milk, but because many macrolides can be excreted through breast milk, so breastfeeding women should be careful with the use of this product, if you have to apply should be suspended when breastfeeding.

5、Children's medication: the efficacy and safety of paediatric patients within 6 months have not been determined.

Elderly patients with normal hepatic and renal functions do not need to reduce the dosage.

Drug interactions of  Bulk Acetylspiramycin Powder.

1, This product does not affect the in vivo metabolism of drugs such as aminophylline.

2, in patients receiving ergot derivative drugs, the simultaneous use of certain macrolides had ergot poisoning, there is no ergot and acetylspiramycin interaction reports, but theoretically there is still this possibility, so acetylspiramycin and ergot should not be taken at the same time.

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