Bulk Raw Materials Fisetin Powder

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Fisetin Powder Usage and Synthesis.

Fisetin is a polymer pharmaceutical raw material. It is a yellow needle crystal, derived from RhussuccedaneaL and Sumac, a plant of Lacertaceae family. Soluble in ethanol, acetone and acetic acid. Almost insoluble in water, ether, benzene, chloroform and petroleum ether. Inhibits the production of prostate cords in fibroblasts from methylcholanthrene transmorphic variant of 3T3 mice, with a half-effective inhibitory concentration (ID50) of 42.0 UM. Inhibits the enzyme allose reductase in the eye lens of rats, with a half-effective inhibitory concentration of 10-6 M. In mouse small intestine specimens, its antispasmodic potency against the spasmolytic action of acetylcholine was 166% of that of poppypine. A group of researchers from Japan and the United States found in animal experiments that lacinin in vegetables and fruits helps to improve memory.

Uses of Fisetin.

Used for content determination/identification/pharmacological experiments, etc. Pharmacological effects.

1.Inhibition of prostaglandins:Inhibits the production of prostaglandin in fibroblasts of 3T3 mice with transmorphic variant of methylcholanthrene, with a half effective inhibitory concentration (ID50) of 42.0UM.

2.Enzyme inhibition:It has inhibitory effect on the whole sugar reductase of rat eye lens, the half effective inhibitory concentration (ID50) is 10-6M.

3. Antispasmodic: the mouse small intestine specimens, the effectiveness of its antispasmodic effect against acetylcholine for the poppy alkaloids 166%.

4. A team of researchers from Japan and the United States found by animal experiments that lacinin in vegetables and fruits helps improve memory.

A naturally occurring flavonol with therapeutic activity is used in the synthesis of pharmacologically active anti-inflammatory, anticonvulsant and antiproliferative drugs.

Pharmacological action of Icariin .

1.Inhibition of prostaglandins:Inhibited the production of prostaglandin in fibroblasts from methylcholanthrene transmorphic variant of 3T3 mice with an inhibitory half effective concentration (ID50) of 42.0UM.

2. Enzyme inhibition: Inhibit the enzyme allose reductase in rat eye lens, the half effective inhibitory concentration (ID50) is 10-6M.

3. Antispasmodic: the mouse small intestine specimens, its antispasmodic effect of acetylcholine for the effectiveness of poppy alkaloids 166%.

4, by Japan, the United States researchers composed of a group of animal experiments found that vegetables and fruits in the laccasein helps to improve memory.

Physical Property of Fisetin Powder.

Yellow needle crystal (dilute ethanol), melting point 330 ℃ (decomposition). Soluble in ethanol, acetone

and acetic acid. Almost insoluble in water, ether, benzene, chloroform and petroleum ether. Melting point 348 ℃, bright yellow fine needle crystal Melting point〉300℃

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