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Product details
Spermidine is a low molecular weight aliphatic carbocation with three amine groups, and is one of the natural polyamines present in all living organisms. It is an important raw material for drug synthesis and is widely used in the synthesis of pharmaceutical intermediates.
Uridine is widely distributed in living organisms and is biosynthesised from putrescine (butylenediamine) and adenosine methionine.
Spermidine maintains cell membrane stability, increases the activity of antioxidant enzymes, and improves the expression of photosystem II (PSII) and related genes.Spermidine also significantly reduces H2O2 and O2.- levels.
Uses and functions of Spermidine.
Spermidine can delay protein senescence. Because different molecular weight proteins may play different roles in the aging process, some large molecular weight proteins may play a key role in controlling the aging process of leaves, and once these proteins begin to degrade, aging is inevitable, and controlling the degradation of these proteins can slow down the process of aging, and the reason why spermidine can delay the aging process may lie in the promotion of the synthesis of these proteins or preventing their degradation.
Inhibits neuronal NO synthase (nNOS). Binds and precipitates DNA; also used to purify DNA-binding proteins. Stimulates T4 polynucleotide kinase activity.
Physiological role of Spermidine.
Spermidine is involved in many biological processes in organisms, such as the regulation of cell proliferation, cellular senescence, organ development, immunity, cancer and other physiological and pathological processes. Recent studies have shown that spermidine plays an important role in the regulation of synaptic plasticity, oxidative stress and autophagy in the nervous system.
Difference between spermidine and NMN.
| Comparison item | Spermidine | NMN |
| Main targets | Autophagy, polyamine metabolism | NAD+ synthesis, Sirtuins activation |
| Core functions | Removal of cellular waste, anti-oxidation | Energy metabolism, DNA repair |
| Research maturity | More animal studies, limited human data | Animal studies are sufficient, human trials are ongoing |
| Applicable population | Those who care about longevity and neurological health | Those who improve fatigue and metabolic declin |
Synthesis method of Spermidine Powder
Uridine is widely distributed in living organisms and is biosynthesised from putrescine (butylenediamine) and adenosine methionine.
FAQ.
Q: Which one is better than NMN/resveratrol?
A: Different mechanisms of action:
NMN: Supplement NAD+ (energy metabolism)
Resveratrol: Activate SIRT1 (gene repair)
Spermidine: The only one that directly activates autophagy → It is recommended to use the three together
Q: Are there any side effects?
A: Clinical studies show:
No serious adverse reactions within the safe dose (<20mg/day)
5% of the population may experience short-term gastrointestinal discomfort (recommended to take with meals)
Q: Why is continuous supplementation necessary?
A: The content in the body drops sharply with age:
30 years old: 60% lower than 20 years old
60 years old: only 15-20% of young people
Clinical case witness
Case 1: 52-year-old male executive
Scheme: 10mg/day (containing resveratrol compound formula)
After 6 months:
✦ Telomere length increased by 17% (SpectraCell test)
✦ Resting heart rate dropped from 78 to 62
✦ Physical examination report showed LDL from 4.2→2.8mmol/L
Case 2: 68-year-old early Alzheimer's patient
Scheme: 15mg/day + Mediterranean diet
After 12 months:
✦ MMSE score from 18→24 points
✦ Brain atrophy slowed by 39% (MRI control)
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