Pharmaceutical Bulk Turkesterone Powder

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Turkesterone Powder Usage and Synthesis.

Turkesterone was isolated from Ajuga turkestanica, a potent ecdysteroid used as an ecdysteroid receptor (EcR) agonist in some insect systems.

Uses and functions of Turkesterone.

Dew grass (CyanotisarachnoideaC.B.Clarke), also known as Pearl Dew grass, Cockscomb Ginseng, etc., the Department of Duck Toe Grass family, the genus of perennial herbaceous plants, widely distributed in Yunnan Province, with the effect of tonifying the deficiency, removing the dampness, soothing the tendons and activating the collaterals, the Turkestanone from the plant for the first time to be isolated!

Pharmacological Effects of Turkesterone.

Preparation method of Bulk Turkesterone Powder.

Dew grass (2.5kg) was extracted with 75% ethanol by heating and refluxing, recovering the ethanol and obtaining the concentrate. Extracted with ethyl acetate, n-butanol; ethyl acetate extract, Al2O3 (neutral) column chromatography, chloroform-methanol gradient elution, chloroform-methanol (4:1) elution part of the ethyl acetate-methanol recrystallisation, to obtain the compound 3 (200mg); 3:1 elution part of the preparative thin-layer chromatography (stationary phase: silica gel GF254; mobile phase: chloroform-methanol = 5:1) to obtain the compound 1 (10mg); eluted with methanol part of the methanol by preparative thin-layer chromatography (stationary phase: silica gel GF254; mobile phase: chloroform-methanol = 5:1) to obtain Compound 1 (10mg); methanol elution by preparative high performance liquid chromatography (ODS, methanol / water = 31:69, 242nm detection) to isolate Turkestanone (5mg)

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