Hrk supply Doxycycline Raw materials powder

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Doxycycline powder of Usage and Synthesis.

1, bacterial disease, used in respiratory tract, such as pleuropneumonia, swine lung disease and other diseases, doxycycline + flufenicol + fever drug effect is good;

2, actinomycetes, that is, pigs can grow in various positions of the pus, in addition to streptococcus pyogenes, there is another situation is caused by actinomycetes, generally doxycycline effect is better;

3, common, "body" disease; Mycoplasma is also wheezing disease, doxycycline + flufenicol (mycoplasma net) effect is good;

4, chlamydia, the first is sow abortion, fetal pearl-like to consider, with doxycin treatment effect is better; The second kind of conjunctivitis, red eyes use tetracycline eye drops eye effect is better;

5, spirochaeta (swine dysentery, etc.), Rickettsia with less, not much to say;

6, the worm, is the blood protozoa, that is, we often say with red body and other diseases, doxycycline administration effect is better;

7, oxytetracycline is generally used in the prevention and treatment of sows, the harm is less and the effect is more moderate; Doxycycline is often used in lactating piglets after seven days, yellow with white, white with gray such feces; Fat pigs in the dog days, often have a fever rebound, repeated.

Uses of Doxycycline.

Doxycycline, also known as doxycycline hydrochloride and deoxyoxyomycin, is a highly efficient, broad-spectrum and low-toxicity semi-synthetic tetracycline antibiotics with similar antibacterial spectrum and oxyomycin, but the effect is 2 to 10 times stronger. At present, it is mainly used in the prevention and treatment of eperythrozoon in pig industry. In addition, it can also be used to treat colibacillosis, salmonellosis mycoplasma disease and psittacosis.

It is a tetracycline broad-spectrum antibacterial and antimycoplasma drug with acidic aqueous solution and good oral absorption. It is easily soluble in water, easy to be affected by metal ions in water and form a complex, forming a red solution and reducing the efficacy of drugs. Therefore, in the selection of the drug, it is very important to choose products with preparation technology and ensure good stability.

In veterinary treatment of livestock and poultry, doxycycline is mainly used to treat respiratory tract infections caused by sensitive bacteria and mycoplasma. Among many pathogenic microorganisms, doxycycline is especially effective against trachea and bronchitis caused by gram-negative bacteria and mycoplasma.

The main reasons for the better effect of doxycycline on trachea and bronchitis in livestock and poultry are its wide antibacterial spectrum and strong antibacterial action. In addition to its good effect on Gram-positive and Gram-negative bacteria, it can inhibit mycoplasma respirans and Rickettsiae pathogens that are resistant to or insensitive to other drugs.

Moreover, doxycycline is absorbed faster after oral administration, and the maximum effect can be achieved about 3h, and the maintenance time in the body is long. Third, doxycycline has certain antitussive, expectorant and wheezing effects, which have been confirmed by animal experiments and are not the characteristics of other antibiotics.

Product Methods of Bulk Doxycycline powder.

The production process of doxycycline is based on oxytetracycline as raw material, and the intermediate 11α-chloro-6-methyloxytetracycline p-toluene sulfonate (referred to as dehydrating substance) is obtained by chlorination and dehydration, and then the dehydrating substance is hydrogenated and reduced to get 6-methyloxytetracycline, and then doxycycline hydrochloride is obtained by ammolysis and salt transfer. The process has the advantages of high yield, friendly environment and stable product quality.

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