Notoginsenoside Raw Materials Powder Notoginsenoside

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Notoginsenoside Powder Usage and Synthesis.

Panax notoginseng is a herb widely used in traditional Chinese medicine. Recent studies have revealed its potential efficacy in beauty and skin care. The active substances in Panax notoginseng, such as saponins and polysaccharides, have whitening, anti-aging and anti-inflammatory effects, making Panax notoginseng one of the research hotspots for cosmetic raw materials.

Panax notoginseng total saponins are the main active ingredients of Panax notoginseng. In particular, in the study of the changes in the chemical composition of raw and cooked Panax notoginseng, the changes in the content of Panax notoginseng saponin R1 and ginsenosides Rg1, Re, Rb1, and Rd have attracted attention. In addition, saponins have been confirmed as the basis of the efficacy of Panax notoginseng and are its main effective active ingredients.

Uses and functions of Notoginsenoside.

1. Improve microcirculation and protect cardiovascular function: In the 1990s, there were studies on the mechanism of NTRl improving cardiovascular disease.

The study said that NTRl has the effect of promoting the synthesis of fibrinolytic system in a variety of vascular-related cells; its mechanism of action may be through the inhibition of endothelial cell E-selectin and neutrophil CD18 protein expression.

Another study showed that NTRl can inhibit the increase of fibronectin level and cell migration of venous endothelial cells caused by TNF_a at the cellular level by inhibiting the activation of ERK and the generation of ROS mediated by NADPH oxidase.

2. Anti-inflammatory effect: Tail vein injection of NTRl can reduce the death of mice caused by lipopolysaccharide (LPS). NTRl can also inhibit the increase of TNF-a caused by LPS in human whole blood cell culture. The latest study found that in the mouse model of lipopolysaccharide-induced cardiac dysfunction, NTRl can inhibit the inflammatory factors of the NF-κB pathway and reduce the inflammatory response and cell apoptosis of the myocardium. This effect may be through upregulating the estrogen receptor a (ERa) and PI3K/Akt pathway.

3. Other effects: NTR1 also has certain anti-tumor and antioxidant effects.

Preparation of Notoginsenoside.

Product method of Bulk Notoginsenoside Powder.

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