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NAD+ (nicotinamide adenine dinucleotide, NAD+ for short) can effectively protect kidney damage caused by renal ischemia, and NAD+ has important application value in the preparation of drugs for the prevention and treatment of renal ischemic damage.
In addition, nicotinamide adenine dinucleotide has certain applications in the preparation of drugs for the treatment of inflammatory pain. NAD+ participates in regulating formalin and complete Freund's adjuvant (CFA)-induced inflammatory pain through NAD+-dependent deacetylases SIRT1 and SIRT2, while SIRT1 and SIRT2 participate in the inhibitory effect of NAD+ on inflammatory pain through different mechanisms, thereby achieving analgesic effect on inflammatory pain.
Uses and functions of nad.
Nicotinamide adenine dinucleotide is a coenzyme drug. It is mainly used in clinical practice for the adjuvant treatment of coronary heart disease and can improve symptoms such as chest tightness and angina pectoris. Adverse reactions occasionally include dry mouth, dizziness, nausea, etc.
It is an essential coenzyme in organisms and is used in biochemical research, clinical diagnosis, clinical drugs and drug research.
Preparation of nad.
Product method of Bulk nad Powder.
Extraction from fresh yeast, the steps are as follows: fresh pressed yeast [crushing, extraction] extract [separation] filtrate [primary adsorption] [elution] primary eluate [neutralization] [secondary adsorption] [elution] [third adsorption] [elution] third eluate [precipitation] [filtration] [drying] coenzyme I
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