Natural Sodium Butyrate Raw materials Powder

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Sodium Butyrate Powder Usage and Synthesis.

Sodium butyrate is a non-antibiotic growth promoting feed additive with multiple effects such as strong food attractant, gastrointestinal physiological regulator, acidifier and electrolyte balance regulator.

Its main effects include:

1. Inhibiting histone deacetylase and inducing cell apoptosis;

2. Promoting the development of intestinal mucosa, repairing mucosal epithelial cells and activating lymphocytes;

3. Adjust the micro-ecological balance of gastrointestinal tract and promote the proliferation of beneficial flora;

4. Reduce piglet diarrhea after weaning, overcome weaning stress and improve piglet survival rate;

5. Enhance feed attractiveness, increase feed intake, and improve animal performance.

Uses of Sodium Butyrate.

Sodium butyrate is a commonly used feed additive, and its main uses include: as a preservative and antioxidant for feed, it can extend the shelf life of feed; as an intestinal health regulator, it can quickly provide energy for intestinal cells, promote the growth and development of small intestinal villi, repair intestinal mucosal damage, regulate the balance of intestinal flora, participate in immune regulation, etc., so as to maintain the health of the intestinal tract; as an acidifier for feed, it can reduce the pH value of feed, inhibit the growth of harmful bacteria and improve the digestion and absorption of feed. As an acidifier of feed, it can reduce the pH value of feed, inhibit the growth of harmful bacteria, and improve the digestibility and absorption rate of feed.

The active ingredient of sodium is short-chain volatile fatty acid-butyric acid, which has the physiological functions of promoting intestinal digestion and absorption, maintaining the balance of organic acid in the body and enhancing immunity.

In vitro studies of Sodium Butyrate.

Butyrate mediates growth inhibition of colon cancer cells, thereby elucidating the molecular link between a high-fiber diet and colon carcinogenesis inhibition.

Butyrate induced the expression of p21 mRNA in an immediate-early manner via a 1.4-kb promoter cis-element (multiple) located at the transcription start site, independent of p53-binding trans-activation.Butyrate induced apoptosis at physiological concentrations in 2 adenoma cell lines, RG/C2 and AA/Cl, as well as in the carcinoma cell line PC/JW/FI.

Butyrate has potent effects on a wide range of colonic mucosa such as inhibiting inflammation and tumorigenesis, enhancing various components of the colonic defense barrier and reducing oxidative stress.Butyrate inhibits most HDACs, except class III HDACs and class II HDACs6 and -10.

It is also the most potent fatty acid for stimulating or inhibiting the expression of specific genes.

Product Method of Bulk Sodium Butyrate Powder.

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