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Chrysoerioline, also known as chrysoerioline, wild indigoine, chrysoerioline, belongs to quinolizidine alkaloids, is a derivative of pyridine, one of the main alkaloids in bitter pea grass, mostly distributed in plants of Leguminosae and Berberidaceae, with multiple pharmacological effects such as anti-arrhythmia, anti-microbial infections, anti-ulcer, elevation of leukocytes and so on.
Clinically, it is mainly used for the rescue of surgical trauma, war wounds and asphyxiating agents, cyanide agents, anaesthetics and other intoxication caused by reflex apnoea and infectious diseases with respiratory and cardiovascular activity of the exhaustion as well as shock, the state of collapse and neonatal asphyxia and other symptoms of the treatment.
Uses of Cytisine powder.
It is used for reflex apnoea, shock and neonatal asphyxia caused by surgery and various traumas.
This class of alkaloids also has antiarrhythmia, anti-microbial infection, anti-ulcer, elevate white blood cells and other aspects of pharmacological effects, especially the stronger anti-cancer activity of this class of compounds. It can be used to produce smoking cessation drugs, emergency medicine, cough medicine.
Chrysin is an antiarrhythmic drug. It can reduce myocardial stress and conductivity, slow down the heart rate and inhibit myocardial contractility.
It is clinically used in the treatment of tachycardia. This product has the effect of reducing myocardial stress, conductivity and contractility, slowing down the heart rate and prolonging the period of inactivity.
It is mainly used for ventricular tachycardia and functional palpitations. It has a contractile effect on the uterus, and can also be used to induce labour and uterine bleeding. It is also used in the preparation of artificial hibernation therapy, such as hibernation compounds.
Pharmacological Effect of Cytisine powder.
1.Respiratory effect of chrysin is similar to that of nicotine, which can reflexly stimulate respiration.
When 0.02mg/kg or 1.5mg/kg was injected intravenously into the femur, it had a strong respiratory stimulating effect on anaesthetised cats, with accelerated heartbeat and a sharp rise in blood pressure, which quickly returned to normal with the disappearance of respiratory stimulating effect.
The respiratory stimulating effect of 0.01mg/kg dose was not only much stronger than that of the same dose of silymarin, but also stronger than that of 5 times (0.3mg/kg) dose of silymarin.
2.Pressurising effect on the cerebral circulation: Injecting 0.1mg/kg into the carotid artery of cats produced a pressurising effect on the cerebral circulation. This effect was inhibited by PgE1 or PgE2, but enhanced by anti-inflammatory pain.
Clinical applications of Bulk Cytisine powder.
Resuscitation of surgical wounds, battle wounds and reflex apnoea in poisoning caused by asphyxiating agents, cyanide agents, anaesthetics, etc., and failure of respiratory and cardiovascular activity in infectious diseases, as well as shock, deficient states and asphyxia in newborns.
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