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Parecoxib Sodium introduction:
Parecoxib Sodium Drug will be very helpful for pain, inflammation and fever problems, China Parecoxib Manufacturer and Supplier Export high-quality pharmaceutical raw materials, CAS: 198470-85-8, MF: C19H19N2NaO4S, Factory Supply Parecoxib Rawder Coxib sodium drug will be of great help to pain, inflammation and fever problems, and can selectively inhibit and reduce the formation of prostaglandins in tissues including endothelial tissues, but has no effect on platelet thromboxane. Parecoxib is the prodrug of valdecoxib, which can selectively inhibit cyclooxygenase-2 (COX-2), inhibit the conversion of arachidonic acid to prostaglandin (PG), and inhibit the synthesis of PG, thereby exerting It has analgesic and anti-inflammatory effects, but the inhibitory effect on COX-1 is not obvious. Therefore, while exerting analgesic and anti-inflammatory effects, it does not affect the gastrointestinal mucosa, platelets and renal functions. Parecoxib sodium is generally used clinically for the treatment of acute pain after moderate or severe surgery. Effect Parecoxib sodium has anti-inflammatory and analgesic effects. Parecoxib sodium has anti-inflammatory and analgesic effects.
Parecoxib Sodium Uses:
Parecoxib Sodium Injection is an analgesic, and its main active ingredient is parecoxib. Parecoxib is the prodrug of valdecoxib. After entering the body, parecoxib will be metabolized into valdecoxib to play a role in the body. Mainly by inhibiting cyclooxygenase-2, which plays an analgesic effect. Due to the relatively high selectivity of this drug, the side effects on the gastrointestinal tract are relatively small compared with other similar drugs. Parecoxib sodium is mainly used for short-term treatment of pain after surgery, and it can play a better analgesic effect. When using it, it should be noted that it is prohibited for patients with active peptic ulcer or gastrointestinal bleeding, and it is also prohibited for patients with hemorrhagic heart failure. It is also not recommended for the treatment of pain after coronary artery bypass surgery. of this drug. In short, parecoxib sodium injection is mainly an analgesic drug, usually used for short-term pain after surgery.
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