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As a traditional Chinese medicine, whether it is a single drug or compound medicine, it is very effective and widely used in clinical application, mostly used in the treatment of appendicitis, sciatica, pelvic infections, etc. It is also one of the common medicines used in traditional Chinese medicine for the treatment of various cancers, such as breast cancer, lung cancer and so on, and it is known as an anticancer Chinese herbal medicine. Saponaria extract mainly contains compounds such as flavonoids, phenols and triterpenoids, which have antibacterial, anti-inflammatory, antiviral, immunomodulatory, anticoagulant and anticancer effects.Proveedor de Materias Primas Botánicas: Extracto en Polvo de Gleditsia Sinensis (Espina de Jabalí Chino)
Uses of Gleditsia Sinensis Extract.Fournisseur de Matières Premières Végétales : Extrait en Poudre de Gleditsia Sinensis (Épine de Savonnier Chinois)
Pharmacological Effect of Gleditsia Sinensis Extract.
1.Anti-tumour effect
Pharmacological experiments show that saponaria has an inhibitory effect on mouse sarcoma 180. This product is clinically used in the treatment of a variety of tumours, also has a certain efficacy, indicating that the antitumor effect of saponaria.
2.Anti-coagulant effect
Soapwort decoction for 7 consecutive days gavage 3.9g (raw drug)/kg, obviously prolong the coagulation time of mice; in vitro experiments 2.33, 6.98, 20.93g/kg obviously inhibit platelet aggregation in rabbits; 7 consecutive days of gavage 3.9g/kg obviously reduce the weight of arterial thrombosis in rats, a single gavage of 15g/kg can be significantly prolonged in rabbits plasma complex calcium clotting time, prothrombinogen time, the white blood clotting time. clay partial thromboplastin time, prothrombin time, enhanced plasma antithrombin activity, no significant effect on rabbit plasma fibrinogen content and euglobulin dissolution time. No significant effect on vasodilatory function.
3.Antibacterial effect
Saponaria extracts of Candida albicans, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa bacteriostatic inhibition is not obvious, compared to Staphylococcus aureus has a certain bacteriostatic inhibition. The lowest antibacterial concentration of the aqueous extract of Saponaria spp. on Staphylococcus aureus is 25.0mg-mL-1; the lowest antibacterial concentration of the ethanol extract of Saponaria spp. on Staphylococcus aureus is 12.5mg-mL-1.
4. Anti-allergic effect
Saponaria extract has the ability to inhibit mast cell-dependent allergic reactions. The aqueous extract of Saponaria senegalensis significantly inhibits local reactions induced by anti-DNPIgE sensitisation in rats, and has a certain inhibitory effect on systemic allergic reactions. In-depth study revealed that this anti-allergic effect was achieved by inhibiting the release of histamine from mast cells.
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